98015-53-3 Usage
Description
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE, also known as Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester, is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals. It is characterized by its chloroformate functional group and tetrachloroethyl moiety, which contribute to its reactivity and potential applications in chemical reactions.
Uses
Used in Pharmaceutical Synthesis:
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE is used as a key intermediate in the synthesis of Doxorubicin (D558000), an antineoplastic agent. It plays a crucial role in the production of this medication, which is used to treat various types of cancer.
Used in Anticancer Applications:
In the synthesis of metabolites of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel, (+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE serves as an essential component. Docetaxel is an antimitotic agent that promotes the assembly of microtubules and inhibits their depolymerization to free tubulin, making it a valuable tool in cancer treatment.
Used in Pharmaceutical Industry:
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE is used as a chemical intermediate for the production of various pharmaceuticals. Its unique properties and reactivity make it a valuable asset in the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 98015-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,0,1 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 98015-53:
(7*9)+(6*8)+(5*0)+(4*1)+(3*5)+(2*5)+(1*3)=143
143 % 10 = 3
So 98015-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C3HCl5O2/c4-1(3(6,7)8)10-2(5)9/h1H/t1-/m0/s1
98015-53-3Relevant articles and documents
2,2-Dichlorovinyl Chloroformate
Bowman, Mark P.,Olofson, R. A.,Senet, Jean-Pierre,Malfroot, Thierry
, p. 2240 - 2243 (1990)
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1,2,2,2-Tetrachloroethyl tert-Butyl Carbonate: A Simple and Efficient Reagent for the tert-Butoxycarbonylation of Amines and Amino Acids
Barcelo, Gerard,Senet, Jean-Pierre,Sennyey, Gerard
, p. 3951 - 3953 (2007/10/02)
The reaction of 1-chloroalkyl carbonates with amines affords good yields of the corresponding carbamates.Application to the BOC protection of amino acids is described.
