475207-59-1 CAS NO.475207-59-1

475207-59-1
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Sorafenib tosylate Basic information

Product Name:	Sorafenib tosylate
Synonyms:	SORAFENIB TOSYLATE;Sorafenib & its intermediates;Sorafinib mesylate;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;Sorafenib Tosylate(Bay 43-9006,Nexavar);2-PyridinecarboxaMide, 4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-, 4-Methylbenzenesulfonate;Sorafenib Tosylate (Nexavar);Sorafenib (Nexavar)
CAS:	475207-59-1
MF:	C21H16ClF3N4O3.C7H8SO3
MW:	637.03
EINECS:
Product Categories:	Bay 43-9006
Mol File:	Mol File

Sorafenib tosylate Chemical Properties

CAS DataBase Reference

475207-59-1(CAS DataBase Reference)

Safety Information

MSDS Information

Sorafenib tosylate Usage And Synthesis

Usage	Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.
Usage	Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively

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