voglibose dosage
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1. The brief introduction of voglibose
Vioglibose is an alpha-Glucosidase inhibitor used as an antidiabetic. It belongs to Miscellaneous;VOGLIBOSE;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals. Postprandial hyperglycemia (PPHG) is primarily due to first phase insulin secretion. Alpha glucosidase inhibitors delay glucose absorption at the intestine level and thereby prevent sudden surge of glucose after a meal. This is why vioglibose can used as an antidiabetic. There are three drugs which belong to this class, acarbose, miglitol and voglibose, of which voglibose is the newest. Voglibose scores over both acarbose and miglitol in terms of side effect profile. But acarbose has an edge over voglibose in terms of efficacy (FPG, PPHG, HBA1c).
2. Mechanism of action/Effect:
Vioglibose's Biological Activity shows that it can orally active α -glucosidase inhibitor (IC 50 values are 3.9 and 6.4 nM at sucrase and maltase respectively). Then it can increases glucagon-like peptide 1 (GLP-1) secretion and decreases food consumption in ob/ob mice, and reduces plasma concentrations of glucose, triglycerides and insulin in Wistar fatty rats. Exhibits antidiabetic and antiobesity activity in vivo. So voglibose effect is lower post-prandial blood glucose levels in patients with diabetes mellitus.
3. The dosage of voglibose
The suitable voglibose dosage is 600 μ g/day, three times one day when you are having a meal. You should insist 4 weeks as a period of treatment. Please be careful because taking more voglibose dose will harm your health. When you are lossing of appetite or increasing exhaust, please go to hospital and see your archiater.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects. Tell your physician as soon as possible if you do not feel well.
Verified Supplier
HANGZHOU HOLYPHARM BIOTECH CO.,LTD
- Country: China (Mainland)
- Year Established: 2009
- Business License:
- Business type: Other
- Integral:
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