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Carbenicillin sodium

Carbenicillin sodium could also be called as Carbenicillin disodium salt or carbenicillin disodium.
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    Carbenicillin sodium, with its CAS registry number 4800-94-6, could also be called as Carbenicillin disodium salt or carbenicillin disodium. With its Molecular formula of C17H16N2Na2O6S and molecular weight of 422.36, Carbenicillin sodium is one kind of white solid, and it is stable under normal temperature and pressure. As to Carbenicillin sodium solubility, it is soluble in water. Besides, its Classification Code are Antibacterial and Drug / Therapeutic Agent. 

    When comes to Carbenicillin sodium usage, it could be applied as broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. If you want to store it, you should keep sealed in dry, cool and well-ventilated place, away from light and heat.

    Carbenicillin sodium Toxicity detailed information are as below.

    Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
    dog LD50 intravenous > 4gm/kg (4000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
    dog LD50 subcutaneous > 4gm/kg (4000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
    monkey LD50 intravenous 9800mg/kg (9800mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

    BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

    SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
    Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 34, Pg. 405, 1975.
    mouse LD50 intracrebral 95500ug/kg (95.5mg/kg)   Chemotherapy Vol. 17, Pg. 1111, 1969.
    mouse LD50 intraperitoneal 7600mg/kg (7600mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
    mouse LD50 intravenous 4500mg/kg (4500mg/kg)   Chemotherapy Vol. 23, Pg. 572, 1975.
    mouse LD50 oral > 12gm/kg (12000mg/kg)   Chemotherapy Vol. 23, Pg. 572, 1975.
    mouse LD50 subcutaneous 9gm/kg (9000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
    rabbit LD50 intravenous > 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
    rabbit LD50 subcutaneous > 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
    rat LD50 intraperitoneal 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
    rat LD50 intravenous 6800mg/kg (6800mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
    rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
    rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.

    And if you need more detailed and technical information, you could refer to some leading suppliers in China. eg. Nanjing Aily Biotechnology Co.,Ltd. This company is one leading producer of Ferrocene carboxylic acid which is experienced in chemical manufacturing and custom synthesis.

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