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Oxiracetam dosage

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    Oxiracetam is a relatively newer drug that has been show to improve cognition both in laboratory and real world testing. As our population increases in age, many of us are no longer prepared to accept the memory loss and loss of brain function that were once though to be an inevitable part of the aging process.

     

    Oxiracetam works in the center of the brain. In studies, Oxiracetam has been proven to substantially improve memory and to significantly raise levels of alertness. More studies are still need to be done on the long term benefits, but it is widely agreed that Oxiracetam does improve concentration and alertness. The overwhelming majority of people who use Oxiracetam experience significant improvement in learning ability, memory, recall and attention span.

     

    Oxiracetam is well absorbed from the gastrointestinal tract with a bioavailability of 68-82% according to one source (E. Perucca et al) and 56% according to another. Peak serum levels are reached within one to three hours after a single 800 mg or 2000 mg oral dosage, with the maximal serum concentration reaching between 19-31 µg/ml at these doses. Oxiracetam is mainly cleared renally and thus 84% is excreted unchanged in the urine. The half-life of oxiracetam in healthy individuals is about 8 hours, whereas it is 10-68 hours in patients with renal impairment. There is some penetration of the blood–brain barrier with brain concentrations reaching 5.3% of that in the blood (measured one hour after a single 2000 mg intravenous dosage). Clearance rates range from 9 to 95 ml/min and steady-state concentrations when 800 mg is given twice daily range from 60 µM to 530 µM. The highest concentrations of oxiracetam is found in the septum pellucidum, followed by the hippocampus, the cerebral cortex and with the lowest concentrations in the striatum after a 200 mg/kg oral dose given to rats.


    Normal Dosage: 2-3 caps or more if desired. This amount can be adjusted according to personal preference.
    1-2 caps if taken with piracetam or aniracetam


     

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