Ticagrelor
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1. What is Ticagrelor ?
Ticagrelor (trade name Brilinta in the US, Brilique and Possia in the EU) is a platelet aggregation inhibitor produced by AstraZeneca. It is also called AR-C 126532XX; AZD 6140; (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol. With the CAS No. 274693-27-5, ticagrelor (brilinta) has the molecular formula of C23H28F2N6O4S and a molecular weight of 522.57. Ticagrelor is a crystalline powder with an aqueous solubility of approximately 10 μg/mL at room temperature. The chemical structure of ticagrelor is:
2.Ticagrelor Usage And Ticagrelor Synthesis
Brilinta (ticagrelor) is a reversibly binding oral adenosine diphosphate (ADP) receptor antagonist. ADP receptor blockade inhibits the action of platelets in the blood, reducing recurrent thrombotic events. Ticagrelor and Aspirin are the prevention of Cardiovascular Events.
Brilinta is a P2Y12 platelet inhibitor indicated to reduce the rate of thrombotic cardiovascular events in patients with acute coronary syndrome. PLATO did not show an advantage of Brilinta compared to clopidogrel for CABG-related bleeding.
Brilinta is supplied as a tablet for oral administration. The recommended initial dose is 180 mg (two 90 mg tablets) loading dose and continue treatment with 90 mg twice daily. After the initial loading dose of aspirin (usually 325 mg), use Brilinta with a daily maintenance dose of aspirin of 75-100 mg. If you want to know more about it, you can ask the company of Hangzhou Holypharm biotech Co.,Ltd., a professional supplier of active pharmaceutical ingredients and intermediates.
3.The side effects of Ticagrelor
Ticagrelor may cause side effects,such as headache, back pain, cough, dizziness, nausea, diarrhea, tiredness. If these happened, please tell your doctor if any of these symptoms are severe or do not go away. There are some other serious side effects including shortness of breath; chest pain; fast, slow, pounding, or irregular heartbeat. If you experience any of these symptoms, call your doctor immediately.
Verified Supplier
HANGZHOU HOLYPHARM BIOTECH CO.,LTD
- Country: China (Mainland)
- Year Established: 2009
- Business License:
- Business type: Other
- Integral:
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