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Aliskiren hemifumarate

What is Aliskiren hemifumarate and Tekturna and its related information.
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    1. What is Aliskiren hemifumarate and Tekturna
    Aliskiren hemifumarate (CAS NO.173334-58-2)
    whose IUPAC Name is (2S,4S,5S,7S)-5-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide is a hemifumarate salt form of Aliskiren. Aliskiren hemifumarate raw material belongs to intermediates. Aliskiren Hemifumarate drug belongs to Renin Inhibitor.

    Tekturna contains aliskiren hemifumarate, a renin inhibitor, that is provided as tablets for oral administration. Aliskiren hemifumarate is chemically described as (2S,4S,5S,7S)-N-(2-carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide hemifumarate and its structural formula is



    2. Other properties of Aliskiren hemifumarate
    Molecular Formula : C64H110N6O16
    Average mass : 1219.588745
    Monoisotopic mass : 1218.797852
    Flash Point : 406.4 °C
    Boiling Point : 748.4 °C at 760 mmHg
    Density : 1.067 g/cm3
    Aliskiren hemifumarate solubility : It is soluble in phosphate buffer, n-octanol, and highly soluble in water.

    3. Aliskiren hemifumarate Manufacturers
    There are much high qualitied Aliskiren hemifumarate Manufacturers all around the world such as HANGZHOU HOLYPHARM BIOTECH CO.,LTD a professional supplier of active pharmaceutical ingredients and intermediates. And when choose a cooperator, please pay more attention to its deliverability and its product purity. Usually, aliskiren hemifumarate is white to off white crystalline powder. And the purity is always range from 98%-99.9%. And all the aliskiren hemifumarate manufacturers will provide good service of transport. The Aliskiren hemifumarate price might be US $0-100 / Kilogram.

     

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