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A-834735 crystalline powder

Purity(HPLC):>99% Molecular Formula: C22H29NO2
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    A-834735 crystalline powder

    CAS Number: 895155-57-4
    Systematic name: 1-(tetrahydropyran-4-ylmethyl)-1H-indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone
    Purity(HPLC):>99%
    Molecular Formula: C22H29NO2
    Formula Weight: 339.5
    Formulation: A crystalline solid

    A-834735 crystalline powder is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist at both the CB1 and CB2 receptors, with a Ki of 12nM at CB1 and 0.21nM at CB2. Replacing the aromatic 3-benzoyl or 3-naphthoyl group found in most indole derived cannabinoids, with the 3-tetramethylcyclopropylmethanone group of A-834,735 and related compounds, imparts significant selectivity for CB2, with most compounds from this group found to be highly selective CB2 agonists with little affinity for CB1.

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