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Dufaston

What is Dufaston (Dydrogesterone) and Dufaston (Dydrogesterone) other informations.
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    1. The brief introduction of Dufaston (Dydrogesterone)
    Dufaston
    (Generic name - Dydrogesterone) in HANGZHOU HOLYPHARM BIOTECH CO.,LTD, also known as 9β,10α-pregna-4,6-diene-3,20-dione, is a steroidal progestin. Duphaston (Dydrogesterone) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus. Dydrogesterone is a potent, orally active progestogen indicated in a wide variety of gynaecological conditions.

    2. The development of Dufaston (Dydrogesterone)
    Dufaston (Dydrogesterone) was first introduced to the market in 1961, and is currently approved in over 100 countries worldwide. 28 million patients rely on this drug. Dydrogesterone is to be withdrawn from the UK market from March 2008 for commercial reasons. Dydrogesterone was licensed for use in several indications,including threatened or recurrent miscarriage, dysfunctional uterine bleeding, and hormone replacement therapy.

    3. Other information about Dufaston (Dydrogesterone)
    Dydrogesterone structure
    and pharmacological effects is similar with endogenous progesterone. Dufaston (Dydrogesterone) is orally active at far lower doses. Furthermore, dydrogesterone is non-androgenic, non-estrogenic, non-corticoid, non-anabolic and is not excreted as pregnanediol. And dydrogesterone side effects is lower than other steroidal progestins. And it may be useful in the treatment of menstrual disorders such as absent, irregular or painful menstrual periods, infertility, premenstrual syndrome and endometriosis.

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