Prodel
- Product Details
- Company Profile
1. The oveview of Prodel
Prodel cas 152-62-5 is the synonym of dydrogesterone which is 9b,10a-Pregna-4,6-diene-3,20-dione(6CI,8CI); 6-Dehydro-9b,10a-progesterone. Prodel is a progestogen hormone and the brand name is duphaston. Prodel was licensed for use in several indications,including threatened or recurrent miscarriage, dysfunctional uterine bleeding, and hormone replacement therapy.
2. The pharmacokinetics of Prodel
Prodel is readily absorbed after oral administration. Tmax values vary between 0.5 and 2.5 hours.
Metabolisation of prodel is virtually complete. The main metabolic reaction is hydrogenation of the 20-keto group, resulting in 20-dihydrodydrogesterone (DHD), another potent progestogen. The levels of the main active metabolite DHD also peak about 1.5 hours after dosing.
Prodel has predictable pharmacokinetics. The single-dose kinetics are linear in the oral dose range of 5–20 mg. The pharmacokinetics do not change during repeated administration of up to 20 mg prodel once daily. Steady state is attained after 3 days of treatment.
In HRT, prodel is administered together with an estrogen. Therefore, the interaction between prodel and estrogens has been assessed, and no clinically significant interaction has been observed.
3. Prodel suppliers & manufactures
HANGZHOU HOLYPHARM BIOTECH CO.,LTD is a prodel suppliers & manufactures. It is a professional supplier of active pharmaceutical ingredients and intermediates; agrochemicals and Veterinary products. They are specialized in contract R&D and custom manufacturing. They have rich experience on a wide range of chemical reactions and fermentation from multi gram scale to hundred tons scale according to customers' requirement. Prodel (Dydrogesterone) can be provied on the purity of 99%. Dydrogesterone raw material can be a powder. The package of it will be on aluminum bag or according to your requirement. Hence, when you are seeking for it, please come to HANGZHOU HOLYPHARM.
Verified Supplier
HANGZHOU HOLYPHARM BIOTECH CO.,LTD
- Country: China (Mainland)
- Year Established: 2009
- Business License:
- Business type: Other
- Integral:
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