1. What is Ixempra (CAS NO.219989-84-1)?

Ixempra is the synonym of Ixabepilone which is a kind of API. The epothilones are isolated from the myxobacterium Sorangium cellulosum. Ixempra can be used to manufacture antineoplastic drug. Anthracycline-based and yew drugs in early stage breast cancer (EBC) auxiliary or neoadjuvant chemotherapy is more and more extensive application, the recurrence patients who is already on the above two kinds of drug resistance can use it. Hence, you can use it to replace them. IXEMPRA (ixabepilone) for injection must be constituted with supplied DILUENT. Ixempra is a semisynthetic analog of epothilone B, a 16-membered polyketide macrolide, with a chemically modified lactam substitution for the naturally existing lactone. The mechanism of action of Ixempra is similar with yew kind. Ixempra can promote tubulin polymerization and inhibit its depolymerized to tumor cell block in G2/M phase and apoptosis occurred. The ixabepilone concentration in constituted solution is 2 mg/mL.

2. Mechanism of Ixempra (CAS NO.219989-84-1)?

The sand horse RON's molecular structure and microtubule protein binding site and yew kind of completely different, the drug treatment of β Ⅲtubulin a expression of yew class resistance breast cancer is still effective, and not easily by adenosine triphosphate combined with box transfer protein transfer out of the tumor cells. Therefore, the sand horse rise to a variety of mechanisms of anthracene ring/yew class resistance susceptibility were lower, for the latter and yew class after treatment of recurrent MBC there are still significant anti-tumor effect.

3. What are the possible side effects of Ixempra (ixabepilone)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; warmth or tingly feeling; difficulty breathing; swelling of your face, lips, tongue, or throat.

4. Who is the Ixempra suppliers or manufacturers?

Ixempra is a kind of epothilone B analog. Its raw material can be provided by HANGZHOU HOLYPHARM BIOTECH CO.,LTD which is a professional supplier of active pharmaceutical ingredients and intermediates; agrochemicals and Veterinary products. It can supply Ixempra on the purity of 99%. It can be packaged according to your demand. Therefore, please come to HANGZHOU HOLYPHARM to buy quality Ixabepilone.