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tigecycline dose

Tigecycline dose when use
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    1. Introduction of Tigecycline

    Tigecycline, with the trade name of Tygacil, has its CAS registry number 220620-09-7. This chemical has its Molecular Formula of C29H39N5O8 and Molecular Weight of 585.65, which is usually applied as the glycylcycline antibiotic in the treatment of infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.

    2. Tigecycline dose when use

    When comes to tygacil dose, it should be used according to different cases. Tygacil is often given to the patients by slow intravenous infusion (30 to 60 minutes). Following are some tigecycline dosage information for your reference.
    1). Usual Adult Dose for Pneumonia. Community acquired: 100 mg IV initial dose, followed by 50 mg IV every 12 hours. Duration: 7 to 14 days, depending on the nature and severity of the infection;
    2). Usual Adult Dose for Intraabdominal Infection. 100 mg IV initial dose, followed by 50 mg IV every 12 hours. Duration: 5 to 14 days, depending on the nature and severity of the infection;
    3). Usual Adult Dose for Skin or Soft Tissue Infection. 100 mg IV initial dose, followed by 50 mg IV every 12 hours. Duration: 5 to 14 days, depending on the nature and severity of the infection;
    4). Usual Adult Dose for Skin and Structure Infection. 100 mg IV initial dose, followed by 50 mg IV every 12 hours. Duration: 5 to 14 days, depending on the nature and severity of the infection.

    And the Tigecycline loading dose and Tigecycline mainteance dose are as below:

      Usual Dose Renal Failure Severe Hepatic Impairment (Child Pugh C)
    Loading Dose 100 mg IV x1 no adjustment needed 100 mg IV x1
    Maintenance Dose 50 mg IV q12h no adjustment needed 25 mg IV q12h

    Above are some examles for your reference, and you could go to some authoritative webs for more tigecycline dosing information, or you could also refer to some professional manufacturers which could provide your detailed tygacil dosing information, such as Hangzhou Holypharm biotech Co.,Ltd. This is one specialized supplier of active pharmaceutical ingredients and intermediates; agrochemicals and Veterinary products. Of course, you should not totally rely on these tigecycline dosage information. For more safety and effect, you'd better consult your own doctor or pharmacist.

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