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Lastacaft

Alcaftadine (CAS No.147084-10-4) is a white to yellow powder with an empirical formula of C19H21N3O and a molecular weight of 307.39. It is also called as Lastacaft; 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-Imidazo[2,1-b](3)benzazepine-3-carboxaldehyde.
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    1. The brief introduction of Lastacaft

    Alcaftadine (CAS No.147084-10-4) is a white to yellow powder with an empirical formula of C19H21N3O and a molecular weight of 307.39. It is also called as Lastacaft; 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-Imidazo[2,1-b](3)benzazepine-3-carboxaldehyde. And it is used to prevent eye irritation brought on by allergic conjunctivitis. It is a sterile, topically administered H1 receptor antagonist containing alcaftadine for ophthalmic use.

    2. The basic properties of Lastacaft

    Structural Formula:                                                                             
    Density: 1.24
    Exact Mass: 307.168462
    MonoIsotopic Mass: 307.168462
    Effective Rotor Count: 2.4
    Conformer Sampling RMSD: 0.6
    Contains: Active: alcaftadine 0.25% (2.5 mg/mL). Preservative: benzalkonium chloride 0.005%. Inactives: edetate disodium; sodium phosphate, monobasic; purified water; sodium chloride; sodium hydroxide and/or hydrochloric acid to adjust pH. 
                                                       

    3. How supplied /storage and handling

    How storage and handing Lastacaft is very important to those who use. Therefor, Hangzhou Holypharm biotech Co.,Ltd., a professional supplier of active pharmaceutical ingredients and intermediates pointed that Alcaftadine (alcaftadine ophthalmic solution) 0.25% is supplied in an opaque, white low-density polyethylene bottle with a white polypropylene cap. And it should stored at 15-25°C (59-77°F).

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