6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one Specification
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1. 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one
With the cas number of 86672-58-4, 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one has synonyms of URB 754, 4H-3,1-Benzoxazin-4-one,6-methyl-2-[(4-methylphenyl)amino]-. 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one was originally described as a potent and selective inhibitor of MAG lipase which selectively raises levels of 2-arachidonoylglycerol (2AG). Subsequent studies have shown that that URB-754 does not inhibit recombinant MAG Lipase and that the original activity was due to a contaminant, bis(methylthio)mercurane, in another commercial source.
2. 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one Specification
The Information of 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one Specification is offered by Shanghai Tangfang Biotechnology Co., Ltd.
Purity: 99%
Appearance: off-white solid
Type: Pharmaceutical Intermediates
Density: 1.23 g/cm3
Melting Point: 238-240 °C
Boiling Point: 434 °C at 760 mmHg
Flash Point: 216.3 °C
3. Use of 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one
6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one is reported to be a potent, noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme.
Verified Supplier
Shanghai Tangfang Biotechnology Co., Ltd.
- Country: China (Mainland)
- Year Established: 2010
- Business type: Manufacturers
- Integral:
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