GINSENOSIDE RB2 (cas 11021-13-9) inhibits epithelial-mesenchymal transition of colorectal cancer cells by suppressing TGF-β/Smad signaling
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Add time:08/17/2019 Source:sciencedirect.com
BackgroundTreating colorectal cancer (CRC) continues to be a clinical challenge. Studies have shown that epithelial-mesenchymal transition (EMT) is a critical step in tumor progression and transforming growth factor-β1 (TGF-β1) signaling has been shown to play a crucial role in EMT. Here, we investigate the inhibition effect of GINSENOSIDE RB2 (cas 11021-13-9), main bioactive component of ginseng, in human colorectal cancer cells via TGF-β1.
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