- Remarkably effective phosphanes simply with a PPh2 moiety: Application to Pd-Catalysed cross-coupling reactions for tetra-ortho-substituted biaryl syntheses
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Chemical equation presented Expanding the horizons of ArPPh2: New applications of triarylphosphane ligands are presented. The Pd-L1 and Pd-L2 complexes offer exceptionally high activity in Suzuki-Miyaura cross-couplings of aryl chlorides. The extremely congested synthesis of tetraortho-substituted biaryl compounds is achieved for the first time by simply using triarylphosphane ligands.
- So, Chau Ming,Chow, Wing Kin,Choy, Pui Ying,Lau, Chak Po,Kwong, Fuk Yee
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supporting information; experimental part
p. 7996 - 8001
(2010/09/05)
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- Suzuki-Miyaura coupling of aryl tosylates catalyzed by an array of indolyl phosphine-palladium catalysts
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A family of indolyl phosphine ligands was applied to Suzuki-Miyaura cross-coupling of aryl tosylates. Catalyst loading can be reduced to 0.2 mol % for coupling of nonactivated aryl tosylate. A challenging example for room temperature coupling is realized. The scope of this highly active Pd/L2 system can be extended to other boron nucleophiles, including trifluoroborate salts and boronate esters. The ligand structural comparisons toward the reactivity in tosylate couplings are also described.
- So, Chau Ming,Lau, Chak Po,Chan, Albert S. C.,Kwong, Fuk Yee
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p. 7731 - 7734
(2008/12/22)
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- A general palladium-catalyzed Suzuki-Miyaura coupling of aryl mesylates
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(Chemical Equation Presented) Catalyze this! The first palladium-catalyzed Suzuki-Miyaura coupling of unactivated aryl mesylates is reported, with not only arylboronic acids, but also other organoboron nucleophiles (see picture; Z=B(OH)2, BF3K, BPin). The reaction conditions are compatible with various common functional groups (R1=alkyl, OMe, CHO, CO, CN, CO2R′, heteroaryl).
- So, Chau Ming,Lau, Chak Po,Kwong, Fuk Yee
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supporting information; scheme or table
p. 8059 - 8063
(2009/04/13)
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