- A gene vaccine carrier, preparation method and application thereof
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The invention discloses a gene vaccine vector, and a preparation method and an application thereof; the gene vaccine vector is a supramolecular hydrogel formed through phosphatase catalysis of a small-molecular peptide; the small-molecular peptide has the structural formula represented by the formula (I), wherein when m=1, n=0, 1, 2 or 3; when n=1, m=1, 2 or 3. The gene vaccine vector after being loaded with DNA has the advantages of strong immunogenicity, large load capacity, no obvious toxicity and injectable immunity. The gene vaccine vector is mild in preparation conditions and simple in process.
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Paragraph 0036; 0038; 0042; 0043
(2017/08/26)
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- Enzyme-controllable F-NMR turn on through disassembly of peptide-based nanospheres for enzyme detection
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The enzyme tyrosinase could trigger the disassembly of peptide-based nanospheres, resulting in F-NMR signal turning on.
- Gao, Jie,Shi, Yang,Wang, Youzhi,Cai, Yanbin,Shen, Jie,Kong, Deling,Yang, Zhimou
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p. 1383 - 1386
(2014/03/21)
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- Self-assembled nanospheres as a novel delivery system for taxol: A molecular hydrogel with nanosphere morphology
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Here we reported on the first example of a Folic acid-based molecular hydrogel with nanosphere morphology as a delivery system for Taxol.
- Wang, Huaimin,Yang, Cuihong,Wang, Ling,Kong, Deling,Zhang, Yongjun,Yang, Zhimou
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supporting information; experimental part
p. 4439 - 4441
(2011/06/27)
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