The invention discloses a polymerase inhibitor preparation method, which comprises: 1) preparing 4-[(3-methoxycarbonyl-2-nitro-benzylidene)-amino]-piperidine-1-tert-butyl formate; 2) preparing 2-(1-tert-butoxycarbonyl-piperidin-4-yl)-2H-indazole-7-methyl
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Paragraph 0010
(2017/12/09)
AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS
Amide substituted indazoles and benzotriazoles as inhibitors of the enzyme poly(ADP-ribose)polymerase(PARP). The compounds of the present invention are useful as mono-therapies in tumors with specific defects in DNA-repair pathways, as enhancers of certai
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Page/Page column 43
(2012/02/02)
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