- Arylpiperidine derivatives and use thereof
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The present invention provides an arylpiperidine derivative of the formula (I) or a pharmaceutically acceptable salt thereof, which has antipsychotic effect: wherein D is a carbon atom or a nitrogen atom, E is a CH group or a nitrogen atom, G is an oxygen atom, a sulfur atom, a nitrogen atom or an NH group, Y1is a hydrogen atom or a halogen atom, n is an integer of 1 to 4, and R1is a group represented by any of the formulas (i) to (iv) defined in the specification.
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Page column 16
(2010/11/30)
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- Substituted azolylmethyl-cyclopropyl-carbinol derivatives
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Plant growth-regulating and fungicidal compounds of the formula STR1 in which Ar represents optionally substituted aryl or optionally substituted heteroaryl, R1 represents hydrogen, alkyl, alkenyl, alkynyl, trialkylsilyl, optionally substituted phenylalkyl or an acyl radical, R2 represents halogen, cyano, thiocyano, alkylcarbonyloxy, alkylcarbonylthio or the groupings --X--R3 and --NR4 R5, R3 represents alkyl, cycloalkyl, alkenyl, alkynyl, hydroxyalkyl, alkylthioalkyl, carboxyalkyl, alkoxycarbonylalkyl, optionally substituted aryl, optionally substituted aralkyl or the radical of the formula STR2 R4 and R3 independently of one another represent hydrogen or alkyl, or R4 and R5, together with the nitrogen atom to which they are bonded, represent an optionally substituted cycloaliphatic ring which can contain further heteroatoms, X represents oxygen, sulphur, an SO group or an SO2 group, or R2 furthermore represents hydrogen when Ar represents optionally substituted heteroaryl, and Y represents nitrogen or a CH group, or addition products thereof with acids or metal salts. Novel intermediates are also shown.
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