133565-45-4

Basic information

• Product Name: FMOC-ASPARTIMOL(OTBU)
• Synonyms: FMOC-ASPARTIMOL(OTBU);FMOC-BETA-T-BUTYL ESTER-L-ASPARTIMOL;(S)-tert-butyl 3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-hydroxybutanoate;Nα-Fmoc-Nγ-tert-butyl-L-asparaginol;Fmoc-L-Aspartimol(OtBu);(S)-tert-Butyl 3-(Fmoc-amino)-4-hydroxybutanoate;Nα-Fmoc-Nγ-tert-butyl-L-asparaginol≥ 98% (HPLC)
• CAS NO: 133565-45-4
• Molecular Formula: C₂₃H₂₇NO₅
• Molecular Weight: 543.65
• Product Categories: Fmoc-Amino acid series
• Mol File: 133565-45-4.mol
• Article Data: 21

Chemical Properties

• Melting Point: 97 °C
• Boiling Point: 598.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.198±0.06 g/cm3(Predicted)
• Storage Temp.: Store at 0°C
• PKA: 10.91±0.46(Predicted)
• CAS DataBase Reference: FMOC-ASPARTIMOL(OTBU)(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-ASPARTIMOL(OTBU)(133565-45-4)
• EPA Substance Registry System: FMOC-ASPARTIMOL(OTBU)(133565-45-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 133565-45-4(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

Upstream product

• 71989-14-5 Fmoc-(tBu)Asp-OH 
• 109-02-4 4-methyl-morpholine 
• 543-27-1 isobutyl chloroformate 
• 1072841-00-9 Fmoc-L-Asp(OtBu)-Bt 
• 86061-01-0 tert-butyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-1-pentafluorophenyl L-aspartate 
• 146803-45-4 N-(fluorenylmethyloxycarbonyl)-L-aspart-α-al β-tert-butyl ester 

Downstream Products

• 468773-43-5 [8-methyl-3-(2-nitrobenzenesulfonyl)-7-oxa-3,8-diazabicyclo[4.2.1]non-2-yl]acetic acid tert-butyl ester 
• 468773-24-2 (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester 
• 468773-33-3 (3S)-3-[but-3-enyl-(2-nitrobenzenesullfonyl)-amino]-4-oxobutyric acid tert-butyl ester 
• 468773-25-3 (3S)-3-[(2-nitrobenzenesullfonyl)-amino]-4-hydroxybutyric acid tert-butyl ester 
• 273216-27-6 tert-Butyl (3S)-3-[(9H-9-fluorenylmethoxy)carbonyl]amino-4-oxo-5-phenylpentanoate 
• 872866-35-8 (S)-3-(9H-fluoren-9-ylmethyloxycarbonylamino)-4-phenylsulfanylbutyric acid tert-butyl ester 
• 273216-16-3 tert-butyl (3S)-3-[(9H)-(9-fluorenyl)methoxycarbonyl]amino-4-oxo-9-phenylnonanoate 
• 273216-01-6 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-7-phenyl-heptanoic acid tert-butyl ester 
• 273216-04-9 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-hydroxy-7-phenyl-heptanoic acid tert-butyl ester 
• 872866-36-9 (S)-3-(2-nitro-4-sulfamoylphenylamino)-4-phenylsulfanylbutyric acid tert-butyl ester 

Relevant articles and documents

Modified Nucleobases with Uniform H-Bonding Interactions, Homo- and Hetero-Basepair Bias, and Mismatch Discrimination

Described herein are divalent nucleobases that each binds two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone, such as in a γ-peptide nucleic acid (γPNA). Also provided are genetic recognition reagents comprising one or more of the divalent nucleobases and a nucleic acid or nucleic acid analog backbone, such as a γPNA backbone. Uses for the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided.

Straightforward Entry to S -Glycosylated Fmoc-Amino Acids and Their Application to Solid Phase Synthesis of Glycopeptides and Glycopeptidomimetics

Streamlined access to S-glycosylated Fmoc-amino acids was developed. The process provides diverse glycosylated modified amino acids in high yield and stereoselectivity taking advantage of the in situ generation of a glycosylthiolate obtained from carbohyd

A facile synthesis and crystallographic analysis of N-protected β-amino alcohols and short peptaibols

A facile, efficient and racemization-free method for the synthesis of N-protected β-amino alcohols and peptaibols using N-hydroxysuccinimide active esters is described. Using this method, dipeptide, tripeptide and pentapeptide alcohols were isolated in high yields. The conformations in crystals of β-amino alcohol, dipeptide and tripeptide alcohols were analysed, with a well-defined type III β-turn being observed in the tripeptide alcohol crystals. This method is found to be compatible with Fmoc-, Boc- and other side-chain protecting groups.