217500-96-4 Usage
Description
Tulathromycin A is a triamide antibiotic belonging to the macrolide class, characterized by its 15-membered macrolide structure and three charged nitro groups. It exists as a balanced mixture of two isomers and is known for its antimicrobial properties. Tulathromycin A is an aminoglycoside and appears as a white solid.
Uses
Used in Veterinary Medicine:
Tulathromycin A is used as a therapeutic agent for the treatment of respiratory diseases in cattle and pigs. It is effective against various bacterial pathogens, including Haemophilus somnus, Mycoplasma bovis, Fusarium necrophorum, Fusarium oxysporum, Actinobacillus pleuropneumoniae, Bacteroides multilocularis, Bordetella bronchiseptica, Mycoplasma pneumoniae, and Haemophilus parasiticus.
Used in Cattle:
Tulathromycin A is used as a treatment for rinderpest caused by Haemolytic rinderpest, polyvalent rinderpest, and infections caused by Mycoplasma bovis. It is also utilized to prevent infections in high-risk calves and to treat bovine foot rot associated with Fusarium necrophorum and Fusarium oxysporum. Additionally, it is effective in treating bovine infectious keratoconjunctivitis (Mycobacterium bovis).
Used in Pigs:
In pigs, Tulathromycin A is used to control and treat Swine Respiratory Disease (SRD) associated with Actinobacillus pleuropneumoniae, Bacteroides multilocularis, Bordetella bronchiseptica, Mycoplasma pneumoniae, and Haemophilus parasiticus. It has also been used to treat lung abscesses in pigs.
Check Digit Verification of cas no
The CAS Registry Mumber 217500-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,7,5,0 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 217500-96:
(8*2)+(7*1)+(6*7)+(5*5)+(4*0)+(3*0)+(2*9)+(1*6)=114
114 % 10 = 4
So 217500-96-4 is a valid CAS Registry Number.
217500-96-4Relevant articles and documents
Synthesis of terramycin
-
Paragraph 0020-0021, (2022/01/08)
The present invention relates to the synthesis of terramycin, specifically (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-[[3S,4S,6R,8R]-8-methoxy-4,8-dimethyl-1,5-dioxa snail [2,5]octyl-6-yl]oxo) 3,5,8,10,12,14-hexamethyl-11-[3,4, 6-Tr
Method for synthesizing oxytetracycline and oxytetracycline phosphate (by machine translation)
-
, (2020/04/22)
Step A product shown in Formula is obtained by dissolving, a product of: Formula I with a product shown by subjecting a product shown II in Formula to a reaction; to obtain a product having a hydroxyl: protection product II as shown in Formula I, and a ca
Preparation method for tulathromycin
-
, (2020/07/02)
The invention provides a preparation method for tulathromycin, and belongs to the technical field of drug synthesis. The method comprises the following steps: mainly by using dihydroerythromycin (9-deoxo-9a-aza-9a-homoerythromycin A) as a raw material, performing a hydroxyl protection reaction, performing a selective oxidation reaction of 4'-hydroxyl to generate a ketone, performing an epoxidationreaction to generate an epoxide, performing deprotection, and performing a ring-opening reaction to introduce n-propylamine to generate the target product tulathromycin. In the method, an oxidizing agent for the selective oxidation reaction of the 4'-hydroxyl is hydrogen peroxide or a Dess-Martin periodinane, so that the method avoids the use of equivalent or excessive amounts of a high-valent metal oxidizing agent, has low costs and mild reaction conditions, and improves the yield and purity of the product.