45121-22-0

Basic information

• Product Name: BOC-D-ABU-OH
• Synonyms: BOC-D-NHCH(CH2CH3)-COOH;BOC-D-AMINOBUTYRIC ACID;BOC-D-ALPHA-ABU-OH;BOC-D-ALPHA-AMINOBUTYRIC ACID;BOC-D-ABU(2)-OH;BOC-D-ABU(ALPHA)-OH;BOC-D-ABU-OH;BOC-D-2-AMINOBUTYRIC ACID
• CAS NO: 45121-22-0
• Molecular Formula: C₉H₁₇NO₄
• Molecular Weight: 203.24
• Mol File: 45121-22-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 334.517 °C at 760 mmHg
• Flash Point: 156.11 °C
• Appearance: Yellow/Liquid
• Density: 1.101
• Storage Temp.: Store at RT.
• Solubility: Soluble in DMF (1mmol in 1ml DMF).
• PKA: 4.00±0.10(Predicted)
• CAS DataBase Reference: BOC-D-ABU-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-ABU-OH(45121-22-0)
• EPA Substance Registry System: BOC-D-ABU-OH(45121-22-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 45121-22-0(Hazardous Substances Data)

Usage

Description

BOC-D-ABU-OH, also known as (R)-2-(Boc-amino)butyric acid, is a white powder chemical compound with specific properties that make it useful in various applications. It is characterized by its reactivity in coupling reactions and its role in the preparation of dyes.

Uses

Used in Chemical Synthesis:
BOC-D-ABU-OH is used as a coupling agent in chemical synthesis for its ability to facilitate the formation of new chemical bonds between molecules. This property is particularly valuable in the creation of complex organic compounds and pharmaceuticals.
Used in Dye Preparation:
In the dye industry, BOC-D-ABU-OH is used as a key component in the preparation of various dyes. Its chemical structure contributes to the development of dyes with specific color properties and stability, making it an essential ingredient in the production process.
Used in Pharmaceutical Industry:
BOC-D-ABU-OH is also utilized in the pharmaceutical industry, where its coupling properties are harnessed to synthesize new drugs and improve the efficacy of existing medications. Its versatility in chemical reactions allows for the development of a wide range of therapeutic compounds.
Used in Research and Development:
Due to its unique chemical properties, BOC-D-ABU-OH is often employed in research and development settings. Scientists and researchers use this compound to explore new reaction pathways, develop innovative materials, and study the fundamental principles of chemical interactions.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2835-81-6 2-aminobutanoic acid 
• 40522-79-0 2-aminobutyric acid hydrochloride 
• 162107-50-8 N-Boc-D-ethynyl glycine 
• 185509-01-7 (S,S)-pseudoephedrine N-Boc-2-D-aminobutyramide 
• 162107-49-5 (R)-tert-butyl (1-hydroxybut-3-yn-2-yl)carbamate 
• 170642-21-4 (S,S)-pseudoephedrine D-2-aminobutyramide 

Downstream Products

• 75244-11-0 N^α-tosyl-N^γ-(tert-butyloxycarbonyl-D-aminobutyryl)-L-diaminobutyric acid benzyl ester 
• 160581-25-9 Boc-D-Abu-N-MeArg(Tos)-Gly-OBzl 
• 160581-25-9 C₃₂H₄₆N₆O₈S 
• 162126-54-7 (R)-2-(t-butoxycarbonylamino)-N-phenyl-butanamide 
• 406938-50-9 Boc-N-D-Abu-L-(Ph)Sec-Sar-OEt 
• 936025-29-5 tert-butyl (R)-1-(2-fluoro-6-nitro-N-phenylbenzamido)-1-oxobutan-2-ylcarbamate 
• 934715-51-2 2-[2-(2-tert-butoxycarbonylamino-butyrylamino)-3-methyl-butyrylamino]-3-phenyl-propionic acid methyl ester 
• 934715-42-1 2-[2-(2-tert-butoxycarbonylamino-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 
• 1076206-35-3 N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-N-[(2,3,5-trifluorophenyl)methyl]glycine ethyl ester 
• 1189747-65-6 tert-butyl (R)-1-((S)-2-(3-chlorobenzylcarbamoyl)pyrrolidin-1-yl)-1-oxobutan-2-ylcarbamate 
• 1189747-75-8 (S)-benzyl 1-((R)-2-(tert-butoxycarbonylamino)butanoyl)pyrrolidine-2-carboxylate 
• 1311138-48-3 1,1-dimethylethyl ((1R)-1-{[(2-{[3-(ethyloxy)-4-methylphenyl]oxy}-5-pyrimidinyl)amino]carbonyl}propyl)carbamate 
• 1311139-26-0 1,1-dimethylethyl {(1R)-1-[({6-[(4-cyano-2-cyclopropylphenyl)oxy]-3-pyridinyl}amino)carbonyl]propyl}carbamate 
• 1311138-27-8 1,1-dimethylethyl ((1R)-1-{[(6-{[3-(1-methylethyl)phenyl]oxy}-3-pyridinyl)amino]carbonyl}propyl)carbamate 

Relevant articles and documents

Enantioselective Deaminative Alkylation of Amino Acid Derivatives with Unactivated Olefins

Herein, we report the first Ni-catalyzed enantioselective deaminative alkylation of amino acid and peptide derivatives with unactivated olefins. Key for success was the discovery of a new sterically encumbered bis(oxazoline) ligand backbone, thus offering a de novo technology for accessing enantioenriched sp3-sp3 linkages via sp3 C-N functionalization. Our protocol is distinguished by its broad scope and generality across a wide number of counterparts, even in the context of late-stage functionalization. In addition, an enantioselective deaminative remote hydroalkylation reaction of unactivated internal olefins is within reach, thus providing a useful entry point for forging enantioenriched sp3-sp3 centers at remote sp3 C-H sites.

FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present inve

Bioproduction of l-2-Aminobutyric Acid by a Newly-Isolated Strain of Aspergillus tamarii ZJUT ZQ013

Abstract: l-2-Aminobutyric acid (l-ABA), an unnatural amino acid, is a key intermediate of several important drugs. Although some methods have been developed to prepare pure chiral l-ABA, there are still many drawbacks, including low catalytic efficiency, cumbersome steps and high cost due to the addition of some expensive catalysts or coenzymes. Herein, with chemical and biological approaches together, we discovered a newly isolated Aspergillus tamarii ZJUT ZQ013 strain containing a microbial lipase which could be employed to resolve racemic methyl N-Boc-2-aminobutyrate to produce l-ABA with high enantioselectivity (e.e.s?>?99.9%, E = 257). Moreover, the subsequent gram scale experiment confrimed that A. tamarii ZJUT ZQ013 could be an attractive biocatalyst for the efficient preparation of optically pure acid. Graphical Abstract: [Figure not available: see fulltext.]