50488-34-1Relevant articles and documents
MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
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Paragraph 00187; 00660, (2021/02/19)
This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.
ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
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Paragraph 0173-0175, (2016/11/21)
A compound including a ligand L according to formula I, a first device and a formulation containing the same are disclosed. In the compound including the ligand L of formula I, R^1 and R^2 are independently selected from group consisting of hydrogen, deuterium, halide, alkyl, cycloalkyl, heteroalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carbonyl, carboxylic acids, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, cyano, and combinations thereof; two adjacent substituents of R^1 or R^2 are optionally joined to form a fused ring; a ligand L is coordinated to transition metal M having an atomic number greater than 40; R^1 represents mono, di, tri, or tetra-substitution, or no substitution; R^2 represents mono, di, or tri-substitution, or no substitution; and at least one substituent of R^1 or R^2 is cyano.COPYRIGHT KIPO 2015
A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation
Peters, Martin,Breinbauer, Rolf
supporting information; experimental part, p. 6622 - 6625 (2011/02/21)
The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridiumcatalyzed C-H activated borylation of arenes with its current scope and limitations are reported.