64137-52-6

Basic information

• Product Name: 1H-Benzimidazole-2-propanamine,N-methyl-(9CI)
• Synonyms: 1H-Benzimidazole-2-propanamine,N-methyl-(9CI);3-(1H-BENZIMIDAZOOL-2-YL)PROPYL]METHYLAMINE;3-(1H-benzimidazol-2-yl)-N-methylpropan-1-amine(SALTDATA: FREE);1H-BenziMidazole-2-propanaMine, N-Methyl-;3-(1H-benziMidazol-2-yl)-N-Methylpropan-1-aMine;3-(1H-benzo[d]imidazol-2-yl)-N-methylpropan-1-amine dihydrochloride;N-[3-(1H-benzimidazol-2-yl)propyl]-N-methylamine dihydrochloride;3-(1H-benzimidazol-2-yl)propyl-methyl-amine
• CAS NO: 64137-52-6
• Molecular Formula: C11H15N3
• Molecular Weight: 189.26
• EINECS: 425-760-4
• Product Categories: BENZIMIDAZOLE
• Mol File: 64137-52-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 401 °C at 760 mmHg
• Flash Point: 196.3 °C
• Appearance: /
• Density: 1.114 g/cm³
• Vapor Pressure: 1.22E-06mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 1H-Benzimidazole-2-propanamine,N-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-2-propanamine,N-methyl-(9CI)(64137-52-6)
• EPA Substance Registry System: 1H-Benzimidazole-2-propanamine,N-methyl-(9CI)(64137-52-6)

Safety Data

• Hazardous Substances Data: 64137-52-6(Hazardous Substances Data)

Usage

General Description

1H-Benzimidazole-2-propanamine, N-methyl-(9CI) is a chemical compound with the molecular formula C11H13N3. It is a derivative of benzimidazole with a methyl substituent at the amine group. 1H-Benzimidazole-2-propanamine,N-methyl-(9CI) has potential applications in medicinal chemistry, particularly as a precursor in the synthesis of various pharmaceuticals and bioactive compounds. Its structural features make it a valuable building block for the development of new drugs and biologically active molecules. Additionally, it can be used as a research tool in the study of biological processes and the development of new therapeutic agents.

InChI:InChI=1/C11H15N3/c1-12-8-4-7-11-13-9-5-2-3-6-10(9)14-11/h2-3,5-6,12H,4,7-8H2,1H3,(H,13,14)

Upstream product

• 116666-62-7 benzyl [3-(2-benzimidazolyl)propyl]methylcarbamate 

Relevant articles and documents

Synthesis and evaluation of α,α′-disubstituted phenylacetate derivatives for T-type calcium channel blockers

We have synthesized and evaluated α,α′-disubstituted phenylacetate derivatives that were designed as T-type calcium channel blockers. Among them, compound 10e (IC50 = 8.17 ± 0.48 nM) showed the most potent T-type calcium current blocking activity and higher potency than Mibefradil (IC50 = 1.34 ± 0.49 μM). The PK profile and subtype selectivity over L-type calcium channel were satisfied for further animal assay using disease model.