64205-12-5 Usage
Description
Z-D-TYR-OH, also known as N-Cbz-D-tyrosine, is an N-Cbz-protected form of D-Tyrosine (T899970). D-Tyrosine is an unnatural isomer of L-Tyrosine (T899975) that possesses various biological activities and potential applications in different fields.
Uses
Used in Pharmaceutical Industry:
Z-D-TYR-OH is used as a chiral precursor for the biosynthesis of inhibitors that exhibit anti-inflammatory effects in humans. Its unique properties make it a valuable compound in the development of new drugs targeting inflammation-related conditions.
Used in Microbiology Research:
Z-D-TYR-OH is used as an antimetabolic agent for studying the metabolic activity of Bacillus subtilis. By inhibiting the growth and development of this bacterium, researchers can gain insights into its metabolic pathways and potentially develop new strategies for controlling its proliferation.
Used in Nutritional Studies:
As an isomer of L-Tyrosine, Z-D-TYR-OH may also be used in nutritional studies to understand the effects of D-amino acids on growth and development in rats and other organisms. This can contribute to a broader understanding of the role of amino acids in biological processes and their potential applications in the field of nutrition.
Check Digit Verification of cas no
The CAS Registry Mumber 64205-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,2,0 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64205-12:
(7*6)+(6*4)+(5*2)+(4*0)+(3*5)+(2*1)+(1*2)=95
95 % 10 = 5
So 64205-12-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H17NO5/c19-14-8-6-12(7-9-14)10-15(16(20)21)18-17(22)23-11-13-4-2-1-3-5-13/h1-9,15,19H,10-11H2,(H,18,22)(H,20,21)/t15-/m1/s1
64205-12-5Relevant articles and documents
Enantioselective Enzymatic Cleavage of N-Benzyloxycarbonyl Groups
Patel, Ramesh N.,Nanduri, Venkata,Brzozowski, David,McNamee, Clyde,Banerjee, Amit
, p. 830 - 834 (2007/10/03)
A new enzymatic process for the enantioselective cleavage of N-benzyloxycarbonyl (Cbz) groups from protected amino acids and related compounds has been developed. The Cbz-deprotecting enzyme was isolated from cell extracts of Sphingomonas paucimobilis SC 16113 and purified to homogeneity. The purified protein has a molecular weight of 155,000 daltons and a subunit size of 44,000 daltons.
PAPAIN-ASSISTED RESOLUTION OF NATURAL AND XENOBIOTIC α-AMINO ACIDS
Moriniere, J. L.,Danree, B.,Lemoine, J.,Guy, A.
, p. 441 - 444 (2007/10/02)
A new and convenient method for the preparation of pure enantiomers of α-amino acids is described.Industrial papain, catalyzes the synthesis of L-Z-amino acid ethyl esters in ethanolic medium, with good yields.These esters are obtained from DL-Z-amino acids with 100percent optical purity.Unreactive D-Z-amino acids are readily isolated from reaction medium.Physical constants of natural and xenobiotic L-Z-amino acid esters and D-Z-amino acids are described.
