799557-86-1 Usage
Description
Pyrimidine, 5-bromo-2-(trifluoromethyl)is a chemical compound belonging to the pyrimidine family. It is characterized by the presence of a bromine atom at the 5th position and a trifluoromethyl group at the 2nd position. Pyrimidine, 5-bromo-2-(trifluoromethyl)is known for its potential applications in various fields, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Pyrimidine, 5-bromo-2-(trifluoromethyl)is used as a key intermediate in the synthesis of pyrimidinone compounds. These compounds have been found to possess Lp-PLA2 inhibitory properties, which are important for the development of drugs targeting various inflammatory and cardiovascular diseases.
In the preparation of pyrimidinone compounds as Lp-PLA2 inhibitors, Pyrimidine, 5-bromo-2-(trifluoromethyl)plays a crucial role in the formation of the final product. The unique structural features of this compound, such as the bromine and trifluoromethyl groups, contribute to the overall activity and selectivity of the resulting pyrimidinone compounds. This makes Pyrimidine, 5-bromo-2-(trifluoromethyl)a valuable component in the development of novel therapeutic agents for the treatment of various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 799557-86-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,9,5,5 and 7 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 799557-86:
(8*7)+(7*9)+(6*9)+(5*5)+(4*5)+(3*7)+(2*8)+(1*6)=261
261 % 10 = 1
So 799557-86-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H2BrF3N2/c6-3-1-10-4(11-2-3)5(7,8)9/h1-2H
799557-86-1Relevant articles and documents
PROCESS FOR PREPARING 1-ARYLSULFONYL-PYRROLIDINE-2-CARBOXAMIDE TRANSIENT RECEPTOR POTENTIAL CHANNEL ANTAGONIST COMPOUNDS AND CRYSTALLINE FORMS THEREOF
-
Paragraph 0450; 0452-0454, (2019/09/12)
The invention relates generally to methods of preparing 1-arylsulfonyl-pyrrolidine-2-carboxamide Transient Receptor Potential channel antagonist compounds of the following structure (I): (I) The invention further relates to solvate and co-crystal polymorphs of crystalline formula (I), and methods of preparation thereof.
