836-59-9

Basic information

• Product Name: 4-[2-(4-BROMOPHENOXY)ETHYL]MORPHOLINE
• Synonyms: 4-[2-(4-BROMOPHENOXY)ETHYL]MORPHOLINE;1-[2-(4-BROMOPHENOXY)ETHYL]-MORPHOLINE;Morpholine, 4-[2-(4-broMophenoxy)ethyl]-
• CAS NO: 836-59-9
• Molecular Formula: C₁₂H₁₆BrNO₂
• Molecular Weight: 286.16
• Product Categories: alkyl bromide
• Mol File: 836-59-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 374.2°C at 760 mmHg
• Flash Point: 180.1°C
• Appearance: /
• Density: 1.358g/cm³
• Vapor Pressure: 8.52E-06mmHg at 25°C
• Refractive Index: 1.547
• PKA: 6.35±0.10(Predicted)
• CAS DataBase Reference: 4-[2-(4-BROMOPHENOXY)ETHYL]MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-BROMOPHENOXY)ETHYL]MORPHOLINE(836-59-9)
• EPA Substance Registry System: 4-[2-(4-BROMOPHENOXY)ETHYL]MORPHOLINE(836-59-9)

Safety Data

• Hazardous Substances Data: 836-59-9(Hazardous Substances Data)

Usage

Uses

4-[2-(4-Bromophenoxy)ethyl]morpholine is a useful intermediate for organic synthesis.

InChI:InChI=1/C12H16BrNO2/c13-11-1-3-12(4-2-11)16-10-7-14-5-8-15-9-6-14/h1-4H,5-10H2

Upstream product

• 106-41-2 4-bromo-phenol 
• 3647-69-6 4-(2-chloroethyl)morpholine hydrochride 
• 110-91-8 morpholine 
• 55162-34-0 1-bromo-4-(2-chloroethoxy)benzene 
• 622-40-2 2-(morpholin-4-yl)ethanol 

Downstream Products

• 151825-62-6 2-(4-chlorophenylmethylene)-3-(2-morpholinoethoxy)phenyl-6-methoxy-2,3-dihydrobenzofuran-3-ol 
• 194935-47-2 1-[4-(2-morpholinoethoxy)phenyl]-2-phenyl-1-selenophen-2-ylbutan-1-ol 
• 690636-28-3 4-(2-( 4-( 4, 4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)morpholine 
• 1038395-62-8 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine 
• 1467060-34-9 4-{2-[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenoxy]ethyl}morpholine 
• 1467060-35-0 6-chloro-5-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-1H-indole-3-carbaldehyde 
• 1467057-63-1 6-chloro-5-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-1H-indole-3-carboxylic acid 
• 1038395-64-0 methyl 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetate 
• 1038395-63-9 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile 
• 897016-82-9 KX2-391 
• 1080645-95-9 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide mesylate 
• 1038395-65-1 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide dihydrochloride 
• 988-43-2 4-{2-[4-(5-methoxy-2-phenyl-3H-inden-1-yl)-phenoxy]-ethyl}-morpholine 

Relevant articles and documents

BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD

The present disclosure provides BET inhibitors of the formula: wherein the variables are defined herein, as well as pharmaceutical compositions thereof. The present disclosure also provides methods of treating a patient comprising administering a bromo- and extra-terminal (BET) domain inhibitor for the treatment of FSHD which modulates DUX4 expression. In some embodiments, the present methods comprise using one or more BET inhibitors as a therapeutic agent for the treatment of FSHD patients including patients who are being treated with one or more palliative treatments such as therapy and/or agents which lead to increased muscle mass.

PHARMACEUTICAL COMPOSITIONS FOR MODULATING A KINASE CASCADE AND METHODS OF USE THEREOF

The invention relates to a pharmaceutical composition comprising 2-(5-(4-(2- mopholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.

Antiinflammation agents

Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.