861841-90-9

Basic information

• Product Name: 1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone
• Synonyms: 1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone;Ethanone, 1-[3-aMino-2-hydroxy-5-(phenylMethoxy)phenyl]-
• CAS NO: 861841-90-9
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.2845
• Mol File: 861841-90-9.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 447.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.246±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.32±0.25(Predicted)
• CAS DataBase Reference: 1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone(861841-90-9)
• EPA Substance Registry System: 1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone(861841-90-9)

Safety Data

• Hazardous Substances Data: 861841-90-9(Hazardous Substances Data)

Usage

General Description

1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone, also known as Kratom alkaloid analog 5' is a chemical compound with a molecular formula of C15H15NO3. It is a synthetic analog of the naturally occurring alkaloid in the plant Mitragyna speciosa, also known as Kratom. 1-(3-aMino-5-(benzyloxy)-2-hydroxyphenyl)ethanone has been identified and studied for its potential pharmacological properties, particularly for its opioid-like effects. It is a phenethylamine derivative with a substituted benzene ring and a ketone group, and has shown potential as an analgesic and a sedative, although more research is needed to fully understand its pharmacological profile and potential applications.

Upstream product

• 100-39-0 benzyl bromide 
• 30992-63-3 5-benzyloxy-2-hydroxyacetophenone 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 861841-94-3 1‐[2-hydroxy-3-nitro-5-(benzyloxy)phenyl]ethanone 

Downstream Products

• 861841-89-6 7-acetyl-5-benzyloxy-3H-benzooxazol-2-one 
• 869478-09-1 8-acetyl-6-(phenylmethoxy)-4H-1,4-benzoxazin-3-one 
• 926319-53-1 8-(bromoacetyl)-6-(phenylmethoxy)-2H-1,4-benzoxazin-3(4H)-one 
• 869478-12-6 8-(2R)-oxirane-6-(phenylmethoxy)-2H-1,4-benzoxazine-3(4H)-one 

Relevant articles and documents

CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE

The invention provides a class of compounds represented by formula (I), having bifunctional active quaternary ammonium salt structure of a β2-adrenoreceptor agonist and an M receptor antagonist, a pharmaceutically acceptable salt, solvate, and optical isomer thereof. A pharmaceutical composition comprising such a compound with quaternary ammonium salt structure, a method for preparing such a compound with quaternary ammonium salt structure and an intermediate thereof, and uses thereof in treating pulmonary disorders are also provided. The compounds of the invention have high selectivity to the M receptor subtype, and have less adverse reaction and lower toxic and side effects in the treatment of pulmonary diseases such as COPD and asthma.

Benzoxazine compound and its preparation methods and application

The invention relates to a benzoxazine compound represented in the following formula 1. The benzoxazine compound can serve as a beta 2 receptor agonist. The formula can be seen from the description.

PROCESS FOR THE MANUFACTURING OF BETA MIMETICS

The invention relates to a method for producing betamimetics of formula (1), wherein in which n represents 1 or 2; R1 represents hydrogen, halogen, C1-4-alkyl or O—C1-4-alkyl; R2 represents hydrogen, halogen, C