Synthetic Communications p. 2687 - 2700 (2000)
Update date:2022-08-04
Topics:
Parrish, Jay P.
Dueno, Eric E.
Kim, Seok-In
Jung, Kyung Woon
Cesium carbonate mediated O-alkylation of carboxylic acids was efficiently carried out under mild in situ conditions to give the corresponding esters exclusively. Chiral templates including α-hydroxy and α-alkoxy acids were also converted to their corresponding esters with no observed racemization.
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