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ChemComm
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DOI: 10.1039/C7CC02946B
COMMUNICATION
Journal Name
17 (a) S. D. Turco, S. Sartini, C. Sentieri, C. Saponaro, T.
Navarra, B. Dario, F. D. Settimo, C. L. Motta and G. Basta,
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A. Nayak, S. K. Guchhait, U. C. Banerjee, P. V. Bharatam and
surrogate of imine or C=O in the fused heteroaromatic
skeleton. The reaction of the ylide with aldehyde and 2-
aminopyridine undergoes via a pathway distinctive from usual
transformations, represents a new method for construction of
pyrimidine, and has enabled to access pyridopyrimidin-4-
imines/ones from readily available starting materials. Versatile
aryl moieties can be easily assembled in the products. The
present approach has potential to pave the way for
preparation of biologically-important 2,3-diaryl substituted
pyridopyrimidin-4-imines/ones. Moreover, the explored
reactivity of nitrile-stabilized quaternary ammonium ylide can
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We gratefully acknowledge financial support from CSIR, New
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for her fellowship. DS is thankful to NIPER for her fellowship.
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