Synthetic Communications p. 1852 - 1857 (2011)
Update date:2022-08-16
Topics:
Soni, Ajay
Dutt, Akhilesh
Sattigeri, Viswajanani
Cliffe, Ian A.
A new and efficient method for the demethylation of 6-membered aza-heterocyclic methyl ethers is described using lithium chloride and para-toluenesulfonic acid. This process is chemoselective for aza-heterocyclic methyl ethers in the presence of aryl methyl ethers.
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