The objective of these two methods was to structure of the urocanic amphiphiles was
evaluate the diffusion of various molecules very close but the membranes led to the fol-
through a lipid membrane. Although the lowing flux or insertion classification: Ester E
structure and the composition of these two 1 Ester Z 11 Amide E. From the results
membranes are different, one a DPPC/choles- obtained and for simplicity, the Langmuir
terol monolayer, the other multilayers of epi- film technique seems to be highly suited to the
dermal lipids, the results obtained in incorpo- primary screening of amphiphilic com-
ration and diffusion studies were similar. The pounds.
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433