Dodecyl chloroformate

Base Information

• Chemical Name: Dodecyl chloroformate
• CAS No.: 24460-74-0
• Molecular Formula: C13H25ClO2
• Molecular Weight: 248.793
• Hs Code.: 29159000
• European Community (EC) Number: 246-272-6
• UNII: JRN953UF5S
• DSSTox Substance ID: DTXSID70179217
• Nikkaji Number: J287.261G
• Wikidata: Q72487253
• Mol file: 24460-74-0.mol

Synonyms:dodecyl carbonochloridate;24460-74-0;Lauryl Chloroformate;Dodecyl chloroformate;Chloroformic Acid Dodecyl Ester;Chloroformic Acid Lauryl Ester;n-dodecyl chloroformate;Carbonochloridic acid, dodecyl ester;JRN953UF5S;EINECS 246-272-6;Laurylchloroformate;UNII-JRN953UF5S;Dodecyl chloroformate, 98%;SCHEMBL335168;DTXSID70179217;MFCD00059483;AKOS015899966;F0223;FT-0718519;Q-201283

Chemical Property of Dodecyl chloroformate

Chemical Property:

• Vapor Pressure: 1.33 mm Hg ( 20 °C)
• Refractive Index: n20/D 1.442(lit.)
• Boiling Point: 302.4 °C at 760 mmHg
• Flash Point: 100.3 °C
• PSA: 26.30000
• Density: 0.964 g/cm³
• LogP: 5.28270
• XLogP3: 6.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 12
• Exact Mass: 248.1543077
• Heavy Atom Count: 16
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

Dodecyl Chloroformate >90.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCOC(=O)Cl

Technology Process of Dodecyl chloroformate

There total 3 articles about Dodecyl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-dodecyl alcohol (112-53-8) + bis(trichloromethyl) carbonate (32315-10-9) → n-dodecyl chloroformate (24460-74-0)

Guidance literature:

With pyridine; In tetrachloromethane; at -15 - 20 ℃;

Reference yield: 67.0%

phosgene (75-44-5) + 1-dodecyl alcohol (112-53-8) → n-dodecyl chloroformate (24460-74-0)

Guidance literature:

With triethylamine; In chloroform;

DOI:10.1002/jps.2600771115

Reference yield:

→ n-dodecyl chloroformate (24460-74-0)

Guidance literature:

/BRN= 1771517/;

upstream raw materials:

phosgene

1-dodecyl alcohol

bis(trichloromethyl) carbonate

Downstream raw materials:

5-Dodecyloxy-3-(4-trifluoromethoxy-phenyl)-3H-(1,3,4)-oxadiazol-2-one

dodecyl (4-(3-oxomorpholin)phenyl)carbamate

2-dodecyloxy-5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazine-6-carboxylic acid benzyl ester

(S)-N-(dodecoxycarbonyl)valine

Refernces

• 1、 Wong,Hungtington,Konishi,Rytting,Higuchi. "Unsaturated cyclic ureas as new nontoxic biodegradable transdermal penetration enhancers I: Synthesis". . p. 967 - 971. Retrieved 1988.
• 2、 -. "COMPOUNDS USEFUL IN HIV THERAPY". Page/Page column 42; 43. . Retrieved 2020/03/24.
• 3、 -. "Sulfoethyl carbonate wetting agents and their use in detergent compositions". . . Retrieved 2008/06/13.