Benzyl Morpholinoacetate

Base Information

• Chemical Name: Benzyl Morpholinoacetate
• CAS No.: 53342-23-7
• Molecular Formula: C13H17NO3
• Molecular Weight: 235.283
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID80434945
• Nikkaji Number: J1.230.797G
• Mol file: 53342-23-7.mol

Synonyms:Benzyl Morpholinoacetate;53342-23-7;Benzyl 2-morpholin-4-ylacetate;Morpholin-4-yl-acetic acid benzyl ester;BENZYL 2-(MORPHOLIN-4-YL)ACETATE;Benzyl 2-morpholinoacetate;SCHEMBL1128242;DTXSID80434945;Morpholin-4-yl-aceticacidbenzylester;AC7554;MFCD16495872;Morpholine-4-acetic acid benzyl ester;SY007995;CS-0453410;FT-0730089

Chemical Property of Benzyl Morpholinoacetate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 344.112oC at 760 mmHg
• Flash Point: 161.914oC
• PSA: 38.77000
• Density: 1.138g/cm3
• LogP: 0.99990
• Storage Temp.: 2-8°C
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 235.12084340
• Heavy Atom Count: 17
• Complexity: 233

Purity/Quality:

98%min ^*data from raw suppliers

Benzyl morpholinoacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CC(=O)OCC2=CC=CC=C2

Technology Process of Benzyl Morpholinoacetate

There total 4 articles about Benzyl Morpholinoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

morpholine (110-91-8,99108-56-2) + Benzyl bromoacetate (5437-45-6) → benzyl morpholino-acetate (53342-23-7)

Guidance literature:

In dichloromethane; for 16h; Ambient temperature;

DOI:10.1021/jm00055a003

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → benzyl morpholino-acetate (53342-23-7)

Guidance literature:

Multi-step reaction with 2 steps

2: benzene

With benzene;

Reference yield:

morpholine (110-91-8,99108-56-2) + Benzyl chloroacetate (140-18-1) → benzyl morpholino-acetate (53342-23-7)

Guidance literature:

With benzene;

upstream raw materials:

morpholine

Benzyl chloroacetate

Benzyl bromoacetate

benzyl alcohol

Downstream raw materials:

morpholin-4-ylacetic acid

Refernces

• 1、 -. "Heterocycle derivatives and drugs". . . Retrieved 2008/06/13.