2-Propenoic acid, 3-(2-furanyl)-, methyl ester, (2E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-(2-furanyl)-, methyl ester, (2E)-
• CAS No.: 58293-85-9
• Molecular Formula: C8H8O3
• Molecular Weight: 152.15
• Mol file: 58293-85-9.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-(2-furanyl)-, methyl ester, (2E)-

Chemical Property:

• PSA: 39.44000
• LogP: 1.46580

Purity/Quality:

(2E)-3-(2-furanyl)-2-Propenoicacidmethylester 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-(2-furanyl)-, methyl ester, (2E)-

There total 43 articles about 2-Propenoic acid, 3-(2-furanyl)-, methyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

furfural (98-01-1) + trimethyl phosphonoacetate (5927-18-4) → methyl 3-(2-furyl)acrylate (58293-85-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/j.bmcl.2005.06.090

Reference yield: 99.0%

3-(fur-2-yl)crotonic acid (539-47-9,15690-24-1) + methyl iodide (74-88-4) → methyl 3-(2-furyl)acrylate (58293-85-9)

Guidance literature:

With IRA 904; In acetonitrile; 2.) 25 deg C, 12 h;

Reference yield: 98.0%

furfural (98-01-1) + Methyl diethylphosphonoacetate (1067-74-9) → methyl 3-(2-furyl)acrylate (58293-85-9)

Guidance literature:

With potassium carbonate; In methanol; at 70 ℃; for 0.166667h;

DOI:10.1016/S0040-4020(01)90785-9

upstream raw materials:

furfural

acetic acid methyl ester

methanol

3-(fur-2-yl)crotonic acid

Downstream raw materials:

methyl 3-(5-nitro-2-furyl)-2-propenoate

methyl 3-(2-furyl)propionate

Refernces

• 1、 Larionova, Natalia A.,Ondozabal, Jun Miyatake,Cambeiro, Xacobe C.. "Reduction of Electron-Deficient Alkenes Enabled by a Photoinduced Hydrogen Atom Transfer". supporting information. p. 558 - 564. Retrieved 2020/12/07.
• 2、 Longwitz, Lars,Spannenberg, Anke,Werner, Thomas. "Phosphetane oxides as redox cycling catalysts in the catalytic wittig reaction at room temperature". . p. 9237 - 9244. Retrieved 2019/10/08.