3,5-DIBROMONITRO BENZENE

Base Information

• Chemical Name: 3,5-DIBROMONITRO BENZENE
• CAS No.: 6311-60-0
• Molecular Formula: C6H3Br2NO2
• Molecular Weight: 280.903
• Hs Code.: 29349990
• Mol file: 6311-60-0.mol

Synonyms:1,3-Dibromo-5-nitrobenzene;3,5-Dibromo-1-nitrobenzene;3,5-Dibromonitrobenzene;NSC 43228;

Chemical Property of 3,5-DIBROMONITRO BENZENE

Chemical Property:

• Vapor Pressure: 0.00359mmHg at 25°C
• Melting Point: 103.0 to 107.0 °C
• Refractive Index: 1.64
• Boiling Point: 290.5 °C at 760 mmHg
• Flash Point: 129.5 °C
• PSA: 45.82000
• Density: 2.101 g/cm³
• LogP: 3.64300
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1,3-Dibromo-5-nitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3,5-DIBROMONITRO BENZENE

There total 41 articles about 3,5-DIBROMONITRO BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,6-dibromo-4-nitroaniline (827-94-1) → 3,5-dibromonitrobenzene (6311-60-0)

Guidance literature:

With sulfuric acid; sodium nitrite; In ethanol;

DOI:10.1016/S0040-4039(97)00140-8

Reference yield: 82.0%

C10H12Br2N4O2 (401631-97-8) → 3,5-dibromonitrobenzene (6311-60-0) + 1,3-dibromo-2-chloro-5-nitro-benzene (20098-47-9)

Guidance literature:

With hydrogenchloride; tetrafluoroboric acid; copper; In acetonitrile; at 60 ℃; for 1h;

DOI:10.1055/s-2001-18072

Reference yield: 79.0%

C10H12Br2N4O2 (401631-97-8) → 3,5-dibromonitrobenzene (6311-60-0) + 1,3-dibromo-2-iodo-5-nitrobenzene (98137-96-3)

Guidance literature:

With hydrogen iodide; In acetonitrile; at 60 ℃; for 13h;

DOI:10.1055/s-2001-18072

upstream raw materials:

ethanol

2,6-dibromo-4,N-dinitro-aniline

4-amino-3,5-dibromo-acetophenone

4-amino-3,5-dibromobenzoic acid

Downstream raw materials:

3,5-dibromoaniline

2,4-dibromobenzoic acid

3,3′,5,5′-tetrabromo-1,1′-azobenzene

N-(3,5-Dibromo-phenyl)-hydroxylamine

Refernces

• 1、 Shao, Hao,Foley, David W.,Huang, Shiliang,Abbas, Abdullahi Y.,Lam, Frankie,Gershkovich, Pavel,Bradshaw, Tracey D.,Pepper, Chris,Fischer, Peter M.,Wang, Shudong. "Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents". supporting information. . Retrieved 2021/02/16.
• 2、 Müller, Philipp,Bon, Volodymyr,Senkovska, Irena,Nguyen, Khoa D.,Kaskel, Stefan. "A bifunctional metal–organic framework platform for catalytic applications". supporting information. p. 382 - 386. Retrieved 2019/01/03.