Lactate

Base Information

• Chemical Name: Lactate
• CAS No.: 113-21-3
• Deprecated CAS: 1927-28-2,859046-34-7
• Molecular Formula: C3H5 O3
• Molecular Weight: 89.0709
• UNII: 13GMT0VU0O
• DSSTox Substance ID: DTXSID10873500
• Nikkaji Number: J291.337B
• Wikidata: Q27895931
• Mol file: 113-21-3.mol

Synonyms:2 Hydroxypropanoic Acid;2 Hydroxypropionic Acid;2-Hydroxypropanoic Acid;2-Hydroxypropionic Acid;Ammonium Lactate;D Lactic Acid;D-Lactic Acid;L Lactic Acid;L-Lactic Acid;Lactate;Lactate, Ammonium;Lactic Acid;Propanoic Acid, 2-Hydroxy-, (2R)-;Propanoic Acid, 2-Hydroxy-, (2S)-;Sarcolactic Acid

Chemical Property of Lactate

Chemical Property:

• Vapor Pressure: 0.015mmHg at 25°C
• Boiling Point: 227.6°Cat760mmHg
• Flash Point: 109.9°C
• PSA: 60.36000
• Density: g/cm³
• LogP: -1.88290
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 89.023869017
• Heavy Atom Count: 6
• Complexity: 53.5

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)[O-])O
• Recent ClinicalTrials: Exploring the Effect of Lactate Administration After Ischemic Stroke on Brain Metabolism
• Recent NIPH Clinical Trials: Results of the in-vitro fertilization under lactate little environment

Technology Process of Lactate

There total 20 articles about Lactate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

D-glucose (50-99-7) → D-lactate anion (72-08-2,113-21-3,311-80-8,1927-28-2,15552-92-8,38140-75-9) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0)

Guidance literature:

With potassium dihydrogenphosphate; oxygen; magnesium sulfate; In water; at 30 ℃; for 77h; pH=Ca. 3.0; Reagent/catalyst; Time; Microbiological reaction;

Reference yield: 63.0%

C8H17O6P + cyclohexylamine (108-91-8,157973-60-9) → C3H7O6P*3C6H13N + D-lactate anion (72-08-2,113-21-3,311-80-8,1927-28-2,15552-92-8,38140-75-9)

Guidance literature:

C₈H₁₇O₆P; With trimethylsilyl bromide; In dichloromethane; Inert atmosphere;

With potassium hydroxide; In water;

cyclohexylamine; In water;

DOI:10.1039/b909241b

Reference yield:

propylene glycol (57-55-6,63625-56-9) → acetate (71-50-1) + hydrogen (1333-74-0) + lactate anion (113-21-3) + carbonate(2-) (3812-32-6)

Guidance literature:

With water; potassium hydroxide; at 60 ℃; Electrolysis;

DOI:10.1016/j.ica.2021.120245

upstream raw materials:

1,1-Dichloroacetone

hydroxy-2-propanone

chloroacetone

acetone

Downstream raw materials:

(C₆H₅)B(OH)(CH₃CH(O)(COO))^(1-)

tetrabutylammonium lactate

propylene glycol

Refernces

• 1、 Guo, Ze-Wang,Ou, Xiao-Yang,Xu, Pei,Gao, Hui-Fang,Zhang, Liao-Yuan,Zong, Min-Hua,Lou, Wen-Yong. "Energy- And cost-effective non-sterilized fermentation of 2,3-butanediol by an engineered: Klebsiella pneumoniae OU7 with an anti-microbial contamination system". . p. 8584 - 8593. Retrieved 2020.
• 2、 Guthrie, J. Peter,Cossar, John,Klym, Alex. "Halogenation of Acetone. A Method for Determining pKas of Ketones in Aqueous Solution, with an Examination of the Thermodynamics and Kinetics of Alkaline Halogenation and a Discussion of the Best Value for the Rate Constant for a "Diffusion-Controlled Reaction". Energetic ...". . p. 1351 - 1360. Retrieved 1984.
• 3、 Mullings, Kadia Y.,Sukdeo, Nicole,Suttisansanee, Uthaiwan,Ran, Yanhong,Honek, John F.. "Ni2 +-activated glyoxalase i from Escherichia coli: Substrate specificity, kinetic isotope effects and evolution within the βαβββ superfamily". . p. 133 - 140. Retrieved 2012.
• 4、 Bellini, Marco,Pagliaro, Maria V.,Marchionni, Andrea,Filippi, Jonathan,Miller, Hamish A.,Bevilacqua, Manuela,Lavacchi, Alessandro,Oberhauser, Werner,Mahmoudian, Jafar,Innocenti, Massimo,Fornasiero, Paolo,Vizza, Francesco. "Hydrogen and chemicals from alcohols through electrochemical reforming by Pd-CeO2/C electrocatalyst". . . Retrieved 2021/01/25.