2,5-Dimethoxybenzyl chloride

Base Information

• Chemical Name: 2,5-Dimethoxybenzyl chloride
• CAS No.: 3840-27-5
• Molecular Formula: C9H11 Cl O2
• Molecular Weight: 186.638
• Hs Code.: 29093090
• Mol file: 3840-27-5.mol

Synonyms:Toluene, a-chloro-2,5-dimethoxy-(6CI,7CI,8CI); 2,5-Dimethoxybenzyl chloride; 2,5-Methoxybenzyl chloride;2-(Chloromethyl)-1,4-dimethoxybenzene; NSC 156147

Chemical Property of 2,5-Dimethoxybenzyl chloride

Chemical Property:

• Vapor Pressure: 0.0118mmHg at 25°C
• Melting Point: 69 °C
• Boiling Point: 269.8°Cat760mmHg
• Flash Point: 105.5°C
• PSA: 18.46000
• Density: 1.13g/cm³
• LogP: 2.44260
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(Chloromethyl)-1,4-dimethoxybenzene ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 2,5-Dimethoxybenzyl chloride

There total 7 articles about 2,5-Dimethoxybenzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,5-dimethoxybenzyl alcohol (33524-31-1) → 2,5-dimethoxybenzyl chloride (3840-27-5)

Guidance literature:

With tetrachloromethane; triphenylphosphine; for 12h; Heating;

Reference yield: 85.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1,4-dimethoxybezene (150-78-7) → 2,5-dimethoxybenzyl chloride (3840-27-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; water; at 50 ℃; for 1h; Temperature;

Reference yield:

2,4,6-trimethyl-pyridine (108-75-8) + 2,5-dimethoxybenzyl alcohol (33524-31-1) → 2,5-dimethoxybenzyl chloride (3840-27-5)

Guidance literature:

With thionyl chloride; In dichloromethane;

upstream raw materials:

1,3-dichloro-5,5-dimethylhydantoin

2,5-dimethoxy toluene

2,5-dimethoxybenzyl alcohol

1,4-dimethoxycyclohexa-1,4-diene

Downstream raw materials:

1,15-bis(2,5-dimethoxyphenyl)-2,5,8,11,14-pentaoxapentadecane

1,18-bis(2,5-dimethoxyphenyl)-2,5,8,11,14,17-hexaoxaoctadecane

2,2'-(2,5,8,11-tetraoxadodecane-1,12-diyl)bis(1,4-dimethoxybenzene)

methyl 4-(4-methoxyphenyl)1,2-dihydro-6-ethoxy-1-(2,5-dimethoxybenzyl)-2-oxoquinoline-3-carboxylate

Refernces

• 1、 -. "Preparation method of 2,5-dimethoxyphenylacetic acid". Paragraph 0021-0024; 0029-0032; 0037-0040. . Retrieved 2021/02/06.
• 2、 Huang, Shaohua,Zhang, Guangye,Knutson, Nicholas S.,Fontana, Matthew T.,Huber, Rachel C.,Ferreira, Amy S.,Tolbert, Sarah H.,Schwartz, Benjamin J.,Rubin, Yves. "Beyond PCBM: Methoxylated 1,4-bisbenzyl[60]fullerene adducts for efficient organic solar cells". supporting information. p. 416 - 424. Retrieved 2016/01/15.