4,7,10,16,19,24,27-heptaoxa-1,13-diazabicyclo[11.8.8]nonacosane

Base Information

• Chemical Name: 4,7,10,16,19,24,27-heptaoxa-1,13-diazabicyclo[11.8.8]nonacosane
• CAS No.: 31255-22-8
• Molecular Formula: C20H40 N2 O7
• Molecular Weight: 420.547
• Mol file: 31255-22-8.mol

Synonyms:Cryptand3.2.2; Cryptand 322

Chemical Property of 4,7,10,16,19,24,27-heptaoxa-1,13-diazabicyclo[11.8.8]nonacosane

Chemical Property:

• Vapor Pressure: 1.76E-12mmHg at 25°C
• Boiling Point: 557.9°C at 760 mmHg
• Flash Point: 153.2°C
• Density: 1.12g/cm³

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,7,10,16,19,24,27-heptaoxa-1,13-diazabicyclo[11.8.8]nonacosane

There total 9 articles about 4,7,10,16,19,24,27-heptaoxa-1,13-diazabicyclo[11.8.8]nonacosane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-[2-[2-[2-aminoethoxy]ethoxy]ethoxy]ethylamine (929-75-9,892154-56-2) + triethylene glycol di-(p-toluenesulfonate) (19249-03-7) → 2.2.2‐crypt (31255-22-8)

Guidance literature:

With sodium carbonate; In acetonitrile; for 168h; Heating;

DOI:10.1016/0040-4039(93)89009-F

Reference yield:

C20H40N2O7*Ca(2+) → 2.2.2‐crypt (31255-22-8)

Guidance literature:

In N,N-dimethyl-formamide; at 25 ℃; Rate constant; also PC;

DOI:10.1021/ja00317a017

Reference yield:

2-[2-[2-[2-aminoethoxy]ethoxy]ethoxy]ethylamine (929-75-9,892154-56-2) → 2.2.2‐crypt (31255-22-8)

Guidance literature:

Multi-step reaction with 5 steps

2: LiAlH₄

3: Et₃N

4: B₂H₆

5: (i) aq. HCl, (ii) ion-exchange resin - form>

With lithium aluminium tetrahydride; triethylamine; diborane;

DOI:10.1016/S0040-4020(01)83409-8

upstream raw materials:

2-[2-[2-[2-aminoethoxy]ethoxy]ethoxy]ethylamine

triethylene glycol di-(p-toluenesulfonate)

3,6-dioxa-1,8-octanoyl dichloride

kryptofix 23

Refernces

• 1、 Cox, B. G.,Truong, Ng van,Schneider, H.. "Alkaline Earth Cryptates: Dynamics and Stabilities in Different Solvents". . p. 1273 - 1280. Retrieved 2007/10/02.