Methyl 2,3-dichlorophenylacetate

Base Information

• Chemical Name: Methyl 2,3-dichlorophenylacetate
• CAS No.: 10328-87-7
• Molecular Formula: C9H8Cl2O2
• Molecular Weight: 219.067
• Hs Code.: 29163500
• DSSTox Substance ID: DTXSID90370486
• Wikidata: Q82157643
• Mol file: 10328-87-7.mol

Synonyms:METHYL 2,3-DICHLOROPHENYLACETATE;10328-87-7;methyl 2-(2,3-dichlorophenyl)acetate;Benzeneacetic acid, 2,3-dichloro-, methyl ester;MFCD04112743;SCHEMBL1626544;DTXSID90370486;AKOS015888179;AS-31338;SY003616;CS-0150716;FT-0742736;A896550

Chemical Property of Methyl 2,3-dichlorophenylacetate

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 0.00539mmHg at 25°C
• Refractive Index: 1.542-1.544
• Boiling Point: 274.5 °C at 760 mmHg
• Flash Point: 112.8 °C
• PSA: 26.30000
• Density: 1.318 g/cm³
• LogP: 2.70890
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 217.9901349
• Heavy Atom Count: 13
• Complexity: 185

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl2,3-dichlorophenylacetate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)CC1=C(C(=CC=C1)Cl)Cl

Technology Process of Methyl 2,3-dichlorophenylacetate

There total 1 articles about Methyl 2,3-dichlorophenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ methyl 2-(2,3-dichlorophenyl)acetate (10328-87-7)

Guidance literature:

2,3-Cl2-Ph-CH2COOH, MeOH;

Reference yield: 82.0%

methyl 2-(2,3-dichlorophenyl)acetate (10328-87-7) + ortho-bromobenzaldehyde (6630-33-7) → C14H8Cl2S

Guidance literature:

With potassium carbonate; sulfur; In N,N-dimethyl-formamide; at 110 ℃; for 16h;

DOI:10.1039/c6ra07730g

Reference yield: 38.0%

methyl 2-(2,3-dichlorophenyl)acetate (10328-87-7) + 4-methylamino-2-methylthiopyrimidine-5-carboxaldehyde (185040-32-8) → 6-(2,3-dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one

Guidance literature:

With potassium fluoride on basic alumina; In N,N-dimethyl acetamide; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.ejmech.2021.113252

Downstream raw materials:

methyl 2-(2,3-dichlorophenyl)-2-methylpropanoate