1-Ethyl-2-methylquinolinium iodide

Base Information

• Chemical Name: 1-Ethyl-2-methylquinolinium iodide
• CAS No.: 606-55-3
• Deprecated CAS: 65882-05-5
• Molecular Formula: C12H14 N . I
• Molecular Weight: 299.154
• Hs Code.: 2933 49 90
• European Community (EC) Number: 210-120-7
• NSC Number: 476
• UNII: 4TYE5J46RY
• DSSTox Substance ID: DTXSID90883465
• Mol file: 606-55-3.mol

Synonyms:606-55-3;1-Ethyl-2-methylquinolinium iodide;1-Ethylquinaldinium iodide;Quinaldine ethiodide;1-ethyl-2-methylquinolin-1-ium iodide;N-Ethylquinaldinium iodide;2-Methylquinoline ethiodide;2-Methyl-1-ethylquinolinium iodide;Quinaldinium, 1-ethyl-, iodide;Quinolinium, 1-ethyl-2-methyl-, iodide;1-ethyl-2-methylquinolin-1-ium;iodide;NSC 476;EINECS 210-120-7;4TYE5J46RY;NSC-476;Quinolinium, 1-ethyl-2-methyl-, iodide (1:1);N-Ethyl-2-methylquinolinium iodide;1-ETHYLQUINALDINIUMIODIDE;MFCD00031829;UNII-4TYE5J46RY;SCHEMBL82245;NSC476;SCHEMBL3729149;YSZC1878;HMS553C14;DTXSID90883465;1-ethyl-2-methylquinolin-1-iumiodide;AKOS001026964;SB68605;AS-58761;1-Ethyl-2-methylquinolinium iodide, 97%;LS-139901;CS-0182951;E0172;FT-0632524;D90450

Chemical Property of 1-Ethyl-2-methylquinolinium iodide

Chemical Property:

• Vapor Pressure: 0.0077mmHg at 25°C
• Melting Point: 244 °C (dec.)(lit.)
• Refractive Index: 1.536
• Boiling Point: 268.4ºC at 760 mmHg
• Flash Point: 106.2ºC
• Density: 0.972g/cm3
• Storage Temp.: Store below +30°C.
• Solubility.: 250g/l
• Water Solubility.: Soluble in Water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 299.01710
• Heavy Atom Count: 14
• Complexity: 167

Purity/Quality:

98%,99%, ^*data from raw suppliers

Quinaldine Ethiodide >99.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Quinolines
• Canonical SMILES: CC[N+]1=C(C=CC2=CC=CC=C21)C.[I-]
• Uses: 1-Ethyl-2-methylquinolinium iodide is used as a precursor in synthesis of carbocyanine dyes.

Technology Process of 1-Ethyl-2-methylquinolinium iodide

There total 3 articles about 1-Ethyl-2-methylquinolinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.1%

2-methylquinoline (91-63-4) + ethyl iodide (75-03-6) → 1-ethyl-2-methylquinolinium iodide (606-55-3)

Guidance literature:

In toluene; for 20h; Reflux;

DOI:10.1039/c4ob00132j

Reference yield:

1-ethyl-2-methyl-1,2-dihydro-quinoline (16768-71-1) → 1-ethyl-2-methylquinolinium iodide (606-55-3)

Guidance literature:

With ethanol; iodine;

DOI:10.1039/jr9540002770

Reference yield:

N-ethylquinolinium iodide (634-35-5) → 1-ethyl-2-methylquinolinium iodide (606-55-3)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether; dimethyl cadmium

2: ethanol; iodine

With diethyl ether; ethanol; iodine; dimethylcadmium;

DOI:10.1039/jr9540002770

upstream raw materials:

2-methylquinoline

ethyl iodide

1-ethyl-2-methyl-1,2-dihydro-quinoline

N-ethylquinolinium iodide

Downstream raw materials:

quinaldine red

N-[2-(1-ethyl-1H-[2]quinolyliden)-ethylidene]-p-toluidine; hydriodide

1,1'-diethyl-2,4-cyanine iodide

Refernces

• 1、 Karthigha,Kalainathan,Hamada, Fumio,Yamada, Manabu,Kondo, Yoshihiko. "Synthesis, growth and third-order nonlinear optical properties of quinolinium single crystal-PCLQI". . p. 33159 - 33169. Retrieved 2016.
• 2、 Long, Lingliang,Yuan, Xiangqi,Cao, Siyu,Han, Yuanyuan,Liu, Weiguo,Chen, Qian,Gong, Aihua,Wang, Kun. "Construction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction". . p. 8462 - 8465. Retrieved 2019.
• 3、 Cao, Yu-Yao,Chen, Li-Li,Guo, Long,Qi, Ya-Lin,Wang, Hai-Rong,Yang, Yu-Shun,Yuan, Dan-Dan,Zhu, Hai-Liang. "Two birds with one stone: a NIR fluorescent probe for mitochondrial protein imaging and its application in photodynamic therapy". supporting information. p. 6068 - 6075. Retrieved 2021/08/12.