2-Amino-1-naphthol

Base Information

• Chemical Name: 2-Amino-1-naphthol
• CAS No.: 606-41-7
• Molecular Formula: C10H9 N O
• Molecular Weight: 159.188
• European Community (EC) Number: 210-117-0
• UNII: 797L65QKKD
• DSSTox Substance ID: DTXSID10209406
• Nikkaji Number: J231.865B
• Wikidata: Q27266727
• Mol file: 606-41-7.mol

Synonyms:2-amino-1-naphthol;2-amino-1-naphthol hydrochloride

Chemical Property of 2-Amino-1-naphthol

Chemical Property:

• PSA: 46.25000
• LogP: 2.70880
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 159.068413911
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

98%min ^*data from raw suppliers

2-Aminonaphthalen-1-ol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=C2O)N

Technology Process of 2-Amino-1-naphthol

There total 32 articles about 2-Amino-1-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-1-naphthol (607-24-9) → 2-amino-1-naphthol (606-41-7)

Guidance literature:

With hydrogenchloride; tin;

Reference yield:

azorubine (3567-69-9) → 2-amino-1-naphthol (606-41-7) + Na(1+)*C10H7O4S(1-)

Guidance literature:

With iridium; hexacyanoferrate(III); In aq. phosphate buffer; at 40 ℃; for 24h; pH=7.5; pH-value; Concentration; Reagent/catalyst; Temperature; Catalytic behavior; Thermodynamic data; Activation energy;

DOI:10.14233/ajchem.2016.19308

Reference yield:

2-Nitroso-1-naphthol (132-53-6) → 2-amino-1-naphthol (606-41-7)

Guidance literature:

With hydrochloride of tin dichloride;

upstream raw materials:

2-diazo-1,2-naphthoquinone

2-Nitroso-1-naphthol

2-nitro-1-naphthol

2-amino-1-naphthol-5-sulfonic acid

Downstream raw materials:

2-p-tolyl-naphtho[2,1-d]oxazole

2-biphenyl-4-yl-naphtho[2,1-d]oxazole

N,N-dimethyl-4-naphtho[2,1-d]oxazol-2-yl-aniline

2-diazo-1,2-naphthoquinone

Refernces

• 1、 Bolognese, Adele,Correale, Gaetano,Manfra, Michele,Lavecchia, Antonio,Novellino, Ettore,Pepe, Stefano. "Antitumor agents. 5. Synthesis, structure - activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-benzopyridophenoxazin-5-ones with potent antiproliferative activity". . p. 5110 - 5118. Retrieved 2007/10/03.
• 2、 Mahmoud, Mohamed Rafat,Hamed, Maher Mohamed Ahmed,Shaker, Ali Mohamed. "Kinetics of Hydrolysis of Some New Heterocyclic Azomethines". . p. 765 - 776. Retrieved 2007/10/02.