Benzophenone, O-methyloxime

Base Information

• Chemical Name: Benzophenone, O-methyloxime
• CAS No.: 3376-34-9
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• European Community (EC) Number: 632-615-0
• NSC Number: 61773
• DSSTox Substance ID: DTXSID30289523
• Nikkaji Number: J105.129F
• Mol file: 3376-34-9.mol

Synonyms:Benzophenone, O-methyloxime;benzophenone O-methyloxime;3376-34-9;Methanone, diphenyl-, O-methyloxime;Benzophenone, methyloxime;Methanone, O-methyloxime;benzophenone-O-methyloxime;Benzophenone- O-methyloxime;SCHEMBL211460;Diphenylmethanone o-methyloxime #;DTXSID30289523;N-methoxy-1,1-diphenyl-methanimine;NSC61773;NSC-61773;AKOS005068192

Chemical Property of Benzophenone, O-methyloxime

Chemical Property:

• Vapor Pressure: 0.000939mmHg at 25°C
• Boiling Point: 313°Cat760mmHg
• Flash Point: 117.4°C
• Density: 0.99g/cm³
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 211.099714038
• Heavy Atom Count: 16
• Complexity: 205

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CON=C(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Benzophenone, O-methyloxime

There total 26 articles about Benzophenone, O-methyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzophenone (119-61-9) + N-methoxylamine hydrochloride (593-56-6) → benzophenone oxime methyl ether (3376-34-9)

Guidance literature:

With pyridine; In ethanol; at 50 ℃; for 24h;

DOI:10.1039/c5ob02320c

Reference yield: 94.0%

O-Methylhydroxylamin (67-62-9) + benzophenone O-tosyloxime (79426-17-8) → benzophenone oxime methyl ether (3376-34-9)

Guidance literature:

In acetonitrile; at 20 ℃; for 17h; Product distribution;

DOI:10.1007/BF00503487

Reference yield: 83.0%

(E)-2-((methoxyimino)(phenyl)methyl)benzoic acid → benzophenone oxime methyl ether (3376-34-9)

Guidance literature:

With copper(I) oxide; 1,10-Phenanthroline; In 1-methyl-pyrrolidin-2-one; water; at 170 ℃; for 0.5h;

DOI:10.1039/c3cc45449e

upstream raw materials:

benzophenone oxime ; sodium salt

methyl iodide

O-Methylhydroxylamin

benzophenone

Downstream raw materials:

Benzhydrylamine

benzophenone

O-Methylhydroxylamin

(E)-(2-nitrophenyl)phenyl methanone O-methyl oxime

Refernces

• 1、 Paul, Amrita,Shah, Sk. Sheriff,Shee, Maniklal,Singh, Amit Kumar,Singh, N. D. Pradeep. "Direct Oxygenation of C-H Bonds through Photoredox and Palladium Catalysis". . p. 3426 - 3439. Retrieved 2020/03/23.
• 2、 Wang, Ning,Liu, Lingling,Xu, Wentao,Zhang, Mengye,Huang, Zhibin,Shi, Daqing,Zhao, Yingsheng. "Rhodium(III)-Catalyzed Oxidative Annulation of Ketoximes with Sulfonamide: A Direct Approach to Indazoles". supporting information. . Retrieved 2019/01/21.