Perfluorotributylamine

Base Information

• Chemical Name: Perfluorotributylamine
• CAS No.: 311-89-7
• Deprecated CAS: 146175-90-8,39289-23-1,69072-86-2,90803-72-8,93792-84-8,1201928-35-9,178463-15-5,1201928-35-9,178463-15-5,39289-23-1,69072-86-2,90803-72-8,93792-84-8
• Molecular Formula: C12F27N
• Molecular Weight: 671.096
• Hs Code.: 29211990
• European Community (EC) Number: 206-223-1
• NSC Number: 3501
• UNII: 3702Y1HQ6O
• DSSTox Substance ID: DTXSID0027141
• Nikkaji Number: J11.843E
• Wikipedia: Perfluorotributylamine
• Wikidata: Q15296722
• Mol file: 311-89-7.mol

Synonyms:FC 43;FC-43(47);fluosol-43;FTBA;oxypherol;perfluorotributylamine

Chemical Property of Perfluorotributylamine

Chemical Property:

• Appearance/Colour: clear colourless liquid
• Vapor Pressure: 1.3 mm Hg ( 25 °C)
• Melting Point: -52 °C
• Refractive Index: n20/D 1.3
• Boiling Point: 177 °C at 760 mmHg
• PKA: -26.84±0.50(Predicted)
• Flash Point: 64.1 °C
• PSA: 3.24000
• Density: 1.758 g/cm³
• LogP: 8.56550
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Sparingly), Methanol (Slightly)
• Water Solubility.: insoluble
• XLogP3: 9.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 28
• Rotatable Bond Count: 9
• Exact Mass: 670.9599594
• Heavy Atom Count: 40
• Complexity: 792

Purity/Quality:

Perfluorotributylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,T
• Hazard Codes: Xi,T
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Halogenated Aliphatic Amines
• Canonical SMILES: C(C(C(F)(F)F)(F)F)(C(N(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F
• Description: Perfluorotributylamine (PFTBA, also termed FC-43) is a common mass calibrant used in GC-MS systems. It is a dense, moderately high-boiling liquid. It is the main component of Fluosol-43, an artificial blood substitute that has been approved by the US Food and Drug Administration for use in cardiac angioplasty. PFTBA is also used as an ingredient in some refrigerants. It is persistent in the atmosphere and a powerful greenhouse gas. In 2013, S. A. Mabury at the University of Toronto used IR spectroscopy data to calculate that PFTBA is the strongest global-warming potential of any compound detected in the atmosphere-7100 times greater than that of CO2.
• Uses: Perfluorotributylamine is used in electronic applications viz. liquid burn-in, testing and vapor phase soldering processes. It acts as an indicator fluid to check the leakage and heat transfer fluid for thermal shock testing. It is an active component in fluosol, which is a substitute for artificial blood and fluorinert coolant liquids. Further, it is used as a solvent for computer disc drive lubrication. In addition to this, it is used as a calibration chemical in gas chromatography.Perfluorotributylamine (PFTBA) is commonly used for the calibration of the mass axes of mass spectrometers, basically in those systems, which use electron ionization (EI). PFTBA may be used as a calibration standard for the gas chromatography-mass spectrometric determination of tramadol in human plasma samples and phthalate esters in water samples.

Technology Process of Perfluorotributylamine

There total 9 articles about Perfluorotributylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.1%

tributyl-amine (102-82-9) → Perfluorotributylamine (311-89-7)

Guidance literature:

With fluorine; sodium fluoride; In 1,1,2-Trichloro-1,2,2-trifluoroethane; at 15 ℃; for 5h;

DOI:10.1016/S0022-1139(03)00146-5

Reference yield:

nonafluorobutyl-bis-(1,2,2,3,3,4,4,4-octafluoro-butyl)-amine → carbon tetrafluoride (75-73-0) + freon-218 (76-19-7) + Hexafluoroethane (76-16-4) + Perfluorotributylamine (311-89-7)

Guidance literature:

With fluorine; at 300 - 410 ℃; for 0.1h; Further byproducts given. Title compound not separated from byproducts;

DOI:10.1016/S0022-1139(98)00351-0

Reference yield:

tributylethylammonium iodide (15066-81-6) → carbon tetrafluoride (75-73-0) + Perfluorotributylamine (311-89-7) + perfluoro{di-n-butyl-ethylamine} (103811-99-0)

Guidance literature:

With hydrogen fluoride; Product distribution; other substituted ammonium salts, electrochemical fluorination;

DOI:10.1016/S0022-1139(00)82195-8

upstream raw materials:

tributyl-amine

tetrabutylammomium bromide

tetrabutylammonium tetrafluoroborate

tributylethylammonium iodide

Downstream raw materials:

perfluoro(2-aza-1-hexene)

heptafluoro-1-nitrosopropane

1-Nitro-heptafluor(n)propan

tetradecafluorohexane

Refernces

• 1、 Haszeldine. "-". . p. 102. Retrieved 1951.
• 2、 Dimitrov. A.,Radeck, W.,Ruediger, St.,Bechstein, O.. "On the electrochemical fluorination of quaternary ammonium compounds. Part 1. Tetraalkyl ammonium salts". . p. 57 - 60. Retrieved 2007/10/02.