DL-beta-Chloro-N,alpha-dimethyl-phenethylamine hydrochloride

Base Information

• Chemical Name: DL-beta-Chloro-N,alpha-dimethyl-phenethylamine hydrochloride
• CAS No.: 25394-33-6
• Molecular Formula: C10H14ClN
• Molecular Weight: 183.681
• DSSTox Substance ID: DTXSID80506833
• Mol file: 25394-33-6.mol

Synonyms:25394-33-6;SCHEMBL4648662;NIOSH/SH1079000;DTXSID80506833;ICZRAESMLGJTOQ-UHFFFAOYSA-N;DL-beta-Chloro-N,alpha-dimethyl-phenethylamine hydrochloride;SH10790000;1-phenyl-1-chloro-2 methylamino propane hydrochloride;1-Chloro-N-methyl-1-phenylpropan-2-amine--hydrogen chloride (1/1);Phenethylamine, beta-chloro-N,alpha-dimethyl-, hydrochloride, DL-

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of DL-beta-Chloro-N,alpha-dimethyl-phenethylamine hydrochloride

Chemical Property:

• Boiling Point: 251.899 °C at 760 mmHg
• PKA: 8.86±0.10(Predicted)
• Flash Point: 106.145 °C
• PSA: 12.03000
• Density: 1.04 g/cm³
• LogP: 2.96530
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 219.0581549
• Heavy Atom Count: 13
• Complexity: 121

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(C1=CC=CC=C1)Cl)NC.Cl

Technology Process of DL-beta-Chloro-N,alpha-dimethyl-phenethylamine hydrochloride

There total 22 articles about DL-beta-Chloro-N,alpha-dimethyl-phenethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ephedrine hydrochloride (50-98-6) → (+)-Chloroephedrine (25394-33-6,73393-61-0,110925-64-9)

Guidance literature:

With thionyl chloride; In chloroform;

DOI:10.1021/ac300503g

Reference yield: 80.0%

Novafed (345-78-8) → (+)-Chloroephedrine (25394-33-6,73393-61-0,110925-64-9) + (-)-Chloroephedrine (25394-33-6,73393-61-0,110925-64-9)

Guidance literature:

With thionyl chloride; In chloroform;

DOI:10.1021/ac300503g

Reference yield: 80.0%

Novafed (345-78-8) → (+)-Chloroephedrine (25394-33-6,73393-61-0,110925-64-9) + (-)-Chloroephedrine (25394-33-6,73393-61-0,110925-64-9)

Guidance literature:

With thionyl chloride; In chloroform;

DOI:10.1021/ac300503g

upstream raw materials:

2-methylamino-1-phenylpropanol

methcathinone

(RS)-1-hydroxy-1-phenylpropan-2-one

2-bromo-1-phenyl-1-propanone

Downstream raw materials:

(1RS,2RS)-2-methylamino-1-phenyl-propylsulfanyl cyanate

(4R,5S)-3,4-dimethyl-5-phenyl-imidazolidin-2-one

(4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one

methamphetamin

Refernces

• 1、 Kurashima, Naoki,Makino, Yukiko,Sekita, Setsuko,Urano, Yasuteru,Nagano, Tetsuo. "Determination of origin of ephedrine used as precursor for illicit methamphetamine by carbon and nitrogen stable isotope ratio analysis". . p. 4233 - 4236. Retrieved 2007/10/03.