1,2-Dipiperidinoethane

Base Information

• Chemical Name: 1,2-Dipiperidinoethane
• CAS No.: 1932-04-3
• Molecular Formula: C12H24N2
• Molecular Weight: 196.336
• Hs Code.: 29333999
• European Community (EC) Number: 217-692-7
• NSC Number: 59292
• UNII: U3M2M6CQR6
• DSSTox Substance ID: DTXSID9062067
• Nikkaji Number: J149.898C
• Wikidata: Q81989821
• Mol file: 1932-04-3.mol

Synonyms:dipiperidinoethane;dipiperidinoethane dibromide

Chemical Property of 1,2-Dipiperidinoethane

Chemical Property:

• Appearance/Colour: clear yellow liquid
• Vapor Pressure: 0.0094mmHg at 25°C
• Melting Point: -1 - -0.5 °C
• Refractive Index: 1.4865-1.4885
• Boiling Point: 264.999 °C at 760 mmHg
• PKA: 9.73±0.10(Predicted)
• Flash Point: 107.698 °C
• PSA: 6.48000
• Density: 0.941 g/cm³
• LogP: 1.83400
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 196.193948774
• Heavy Atom Count: 14
• Complexity: 128

Purity/Quality:

99%, ^*data from raw suppliers

1,2-Dipiperidinoethane 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22-22
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CCN2CCCCC2

Technology Process of 1,2-Dipiperidinoethane

There total 27 articles about 1,2-Dipiperidinoethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

piperidine (110-89-4) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → 1,2-dipiperidinoethane (1932-04-3)

Guidance literature:

at 100 ℃; for 5h;

DOI:10.1134/S1070427209090134

Reference yield: 85.0%

piperidine (110-89-4) + ethylene dibromide (106-93-4) → 1,2-dipiperidinoethane (1932-04-3)

Guidance literature:

for 6h; Reflux; Inert atmosphere;

DOI:10.1016/j.tet.2013.07.056

Reference yield: 79.0%

1-[2-(1H-1,2,3-benzotriazol-1-yl)-1,2-bis(piperidin-1-yl)ethyl]-1H-1,2,3-benzotriazole (151257-52-2) → 1,2-dipiperidinoethane (1932-04-3)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jo00297a042

upstream raw materials:

piperidine

ethylene dibromide

N-methylcyclohexylamine

ethylene glycol

Downstream raw materials:

N-methylcyclohexylamine

N-Formylpiperidine

[Pd(pentafluorophenolato)2(1,2-dipiperidinoethane)]

[Ni(3,5-heptanedionate)(1,2-dipiperidinoethane)]BPh₄

Refernces

• 1、 Zheng, Jun,Liu, Feng,Lin, Yichao,Zhang, Zhijie,Zhang, Guangchun,Wang, Lu,Liu, Yan,Tang, Tao. "Synthesis of diverse well-defined functional polymers based on hydrozirconation and subsequent anti-Markovnikov halogenation of 1,2-polybutadiene". . p. 1190 - 1197. Retrieved 2012.
• 2、 Paris, Cecilia,Martín, Nuria,Martínez-Triguero, Joaquín,Moliner, Manuel,Corma, Avelino. "Synthesis of Al-MTW with low Si/Al ratios by combining organic and inorganic structure directing agents". . p. 4140 - 4145. Retrieved 2016/06/09.