Technology Process of Cefoxitin sodium salt, analytical standard
There total 8 articles about Cefoxitin sodium salt, analytical standard which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium lactate;
In
acetone;
at 30 ℃;
for 0.166667h;
Reagent/catalyst;
- Guidance literature:
-
isocyanate de chlorosulfonyle; C15H16N2O6S2;
In
tetrahydrofuran;
at -40 - -37 ℃;
for 0.75h;
With
sodium lactate;
In
methanol; acetone;
at 10 - 12 ℃;
for 2h;
Temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: methanesulfonic acid; N-Bromosuccinimide / dichloromethane; methanol / 2 h / -20 °C
1.2: 2 h / 0 °C / pH 6.5
2.1: sodium hydroxide / methanol; water / pH 10
2.2: 25 °C
3.1: tetrahydrofuran / Cooling
4.1: sodium lactate / acetone / 0.17 h / 30 °C
With
N-Bromosuccinimide; methanesulfonic acid; sodium lactate; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water; acetone;