1-(4-Hydroxyphenyl)-2-phenylethan-1,2-dion

Base Information

• Chemical Name: 1-(4-Hydroxyphenyl)-2-phenylethan-1,2-dion
• CAS No.: 38469-73-7
• Molecular Formula: C14H10 O3
• Molecular Weight: 226.232
• Hs Code.: 2914501900
• Mol file: 38469-73-7.mol

Synonyms:Benzil,4-hydroxy- (6CI,7CI); Ethanedione, (4-hydroxyphenyl)phenyl- (9CI);4-Hydroxybenzil; NSC 115560; p-Hydroxybenzil

Chemical Property of 1-(4-Hydroxyphenyl)-2-phenylethan-1,2-dion

Chemical Property:

• Vapor Pressure: 8.9E-08mmHg at 25°C
• Melting Point: 129-130 °C
• Boiling Point: 423.7°Cat760mmHg
• PKA: 6.41±0.15(Predicted)
• Flash Point: 224.2°C
• PSA: 54.37000
• Density: 1.265g/cm³
• LogP: 2.45780

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-Hydroxyphenyl)-2-phenylethan-1,2-dion

There total 25 articles about 1-(4-Hydroxyphenyl)-2-phenylethan-1,2-dion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-methoxybenzil (22711-21-3) → 1-(4-hydroxyphenyl)-2-phenylethan-1,2-dione (38469-73-7)

Guidance literature:

With sodium; diphenyldisulfane; In 1-methyl-pyrrolidin-2-one; for 0.25h; Heating;

DOI:10.1021/jo010611p

Reference yield: 95.0%

1-(4-Hydroxyphenyl)-2-phenylethanone (2491-32-9) → 1-(4-hydroxyphenyl)-2-phenylethan-1,2-dione (38469-73-7)

Guidance literature:

With selenium(IV) oxide; In 1,4-dioxane; water; for 33h; Heating;

Reference yield: 92.0%

C16H16O4 → 1-(4-hydroxyphenyl)-2-phenylethan-1,2-dione (38469-73-7)

Guidance literature:

With β‐cyclodextrin; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In water; acetone; at 60 ℃; for 15h; Green chemistry;

DOI:10.1039/c5gc01785h

upstream raw materials:

4-methoxybenzil

1-(4-Hydroxyphenyl)-2-phenylethanone

4-(2-phenylethynyl)phenol

[2-(4-Hydroxy-phenyl)-[1,3]dithian-2-yl]-phenyl-methanone oxime

Downstream raw materials:

2-Hydroxy-2-(4-hydroxyphenyl)-1-phenylethanone

(2-hydroxy-1-(4-hydroxyphenyl)-2-phenylethanone)

4-Hydroxy-benzilsaeure

5-(4-hydroxyphenyl)-5-phenyl-2-thiohydantoin

Refernces

• 1、 Charpe, Vaibhav Pramod,Hwang, Kuo Chu,Sagadevan, Arunachalam. "Visible light-induced aerobic oxidation of diarylalkynes to α-diketones catalyzed by copper-superoxo at room temperature". supporting information. p. 4426 - 4432. Retrieved 2020/08/10.
• 2、 Kim, Seung Woo,Um, Tae-Woong,Shin, Seunghoon. "Metal-Free Iodine-Catalyzed Oxidation of Ynamides and Diaryl Acetylenes into 1,2-Diketo Compounds". supporting information. p. 4703 - 4711. Retrieved 2018/04/26.