3,4-Dihydroxypyridine

Base Information

• Chemical Name: 3,4-Dihydroxypyridine
• CAS No.: 10182-48-6
• Molecular Formula: C5H5NO2
• Molecular Weight: 111.1
• Hs Code.: 2933399090
• European Community (EC) Number: 801-036-7
• UNII: UW0C50CU4H
• DSSTox Substance ID: DTXSID50274234
• Nikkaji Number: J557.997J,J743.978D
• Wikidata: Q27891533
• Metabolomics Workbench ID: 51789
• ChEMBL ID: CHEMBL310900
• Mol file: 10182-48-6.mol

Synonyms:3,4-dihydroxypyridine

Chemical Property of 3,4-Dihydroxypyridine

Chemical Property:

• Vapor Pressure: 0.000895mmHg at 25°C
• Refractive Index: 1.593
• Boiling Point: 509.781 °C at 760 mmHg
• PKA: 8.02±0.18(Predicted)
• Flash Point: 262.106 °C
• PSA: 53.35000
• Density: 1.397 g/cm³
• LogP: 0.49280
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 111.032028402
• Heavy Atom Count: 8
• Complexity: 169

Purity/Quality:

99.5% ^*data from raw suppliers

3,4-Dihydroxypyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CNC=C(C1=O)O

Technology Process of 3,4-Dihydroxypyridine

There total 6 articles about 3,4-Dihydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

3-HYDROXYPYRIDINE (109-00-2) → dihydroxypyridine (16867-04-2) + 3,4-dihydroxypyridine (10182-48-6)

Guidance literature:

In various solvent(s); at 28 ℃; for 48h; the root-form rhodococcus opacus (the M form) bacteria;

DOI:10.1007/BF00531557

Reference yield: 9.0%

3-HYDROXYPYRIDINE (109-00-2) → 3-hydroxypyridine N-oxide (6602-28-4) + dihydroxypyridine (16867-04-2) + 3,4-dihydroxypyridine (10182-48-6) + 1,2-dihydro-2,3-dihydroxypyridine

Guidance literature:

In various solvent(s); at 28 ℃; for 48h; pseudomonas fluorescens PfE₁ bacteria;

DOI:10.1007/BF00531557

Reference yield:

4-hydroxy-3-methoxypyridine (62885-41-0) → 3,4-dihydroxypyridine (10182-48-6)

Guidance literature:

With hydrogenchloride; at 145 ℃;

DOI:10.1021/ja01199a068

upstream raw materials:

4-hydroxy-3-methoxypyridine

4,5-dihydroxypyridine-2-carboxylic acid

3-HYDROXYPYRIDINE

Downstream raw materials:

Pyridin-3,4-diol-diacetat

4-bromo-3-hydroxypyridine

L-mimosine

Refernces