4-ACETOXY-2-BUTANONE TECH. 90

Base Information

• Chemical Name: 4-ACETOXY-2-BUTANONE TECH. 90
• CAS No.: 10150-87-5
• Molecular Formula: C6H10 O3
• Molecular Weight: 130.144
• Hs Code.: 2915390090
• Mol file: 10150-87-5.mol

Synonyms:2-Butanone,4-hydroxy-, acetate (6CI,7CI,8CI); 1-Acetoxybutan-3-one; 3-Oxobutyl acetate;4-Acetoxy-2-butanone; NSC 78935

Chemical Property of 4-ACETOXY-2-BUTANONE TECH. 90

Chemical Property:

• Vapor Pressure: 0.717mmHg at 25°C
• Refractive Index: n20/D 1.422(lit.)
• Boiling Point: 184.9°Cat760mmHg
• Flash Point: 69.6°C
• PSA: 43.37000
• Density: 1.015g/cm³
• LogP: 0.52860
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Acetoxy-2-butanone ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ACETOXY-2-BUTANONE TECH. 90

There total 33 articles about 4-ACETOXY-2-BUTANONE TECH. 90 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

butane-1,3-diol 1-acetate (1851-86-1) → 1-acetoxybutan-3-one (10150-87-5)

Guidance literature:

With palladium diacetate; oxygen; triethylamine; In tetrahydrofuran; toluene; at 20 ℃; for 18h;

DOI:10.1021/jo0482211

Reference yield: 89.0%

1-Hydroxy-3-butanone (590-90-9) + acetic anhydride (108-24-7) → 1-acetoxybutan-3-one (10150-87-5) + dimethylglyoxal (431-03-8)

Guidance literature:

With cobalt(II) chloride; In acetonitrile; at 80 ℃;

DOI:10.1021/jo00033a020

Reference yield: 89.0%

1-Hydroxy-3-butanone (590-90-9) + acetic anhydride (108-24-7) → 1-acetoxybutan-3-one (10150-87-5)

Guidance literature:

CoCl₂; In acetonitrile; for 2h; Ambient temperature;

DOI:10.1039/c39870000114

upstream raw materials:

3-buten-1-yne

Ketene

1-Hydroxy-3-butanone

but-2-yn-1-yl acetate

Downstream raw materials:

mevalonolactone

butane-1,3-diol 1-acetate

ethyl 2-carbethoxy-5-oxocaproate

5-methyl-5-nitrohexan-2-one

Refernces

• 1、 Markevich, V. S.,Stepanova, G. A.,Kirichenko, G. S.,Sidorov, V. I.,Ermolaev, A. V.. "SYNTHESIS OF γ-ACETOPROPYL ALCOHOL FROM γ-BUTYROLACTONE AND ACETIC ACID". . p. 908 - 912. Retrieved 1982.
• 2、 Morgan,Holmes. "-". . p. 2667,2671. Retrieved 1932.
• 3、 Cornforth et al.. "-". . p. 311,326. Retrieved 1959.
• 4、 -. "METHOD FOR MANUFACTURING KETONE". Page/Page column 7; 8-9. . Retrieved 2012/08/08.
• 5、 Dewan, Anindita,Bora, Utpal,Kakati, Dilip Kumar. "A facile and efficient method for catalytic acetylation of alcohols with acetic acid". experimental part. p. 3870 - 3871. Retrieved 2011/09/16.